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CAS 363-24-6

:

Prostaglandin E2

Description:
Prostaglandin E2 (PGE2) is a bioactive lipid compound that plays a crucial role in various physiological processes, including inflammation, pain modulation, and regulation of blood flow. It is classified as a prostaglandin, which is a group of lipid compounds derived from fatty acids. PGE2 is synthesized from arachidonic acid through the action of cyclooxygenase enzymes. This compound is characterized by its ability to bind to specific receptors (EP receptors) that mediate its diverse biological effects. PGE2 is involved in the modulation of immune responses, gastrointestinal function, and reproductive processes. It is also known to influence the regulation of body temperature and the maintenance of renal blood flow. Due to its significant role in inflammatory responses, PGE2 is a target for therapeutic interventions in conditions such as arthritis, cancer, and cardiovascular diseases. Its chemical structure includes a cyclopentane ring and multiple functional groups, contributing to its reactivity and biological activity. Overall, PGE2 is a vital mediator in many physiological and pathological processes within the body.
Formula:C20H32O5
InChI:InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1
InChI key:InChIKey=XEYBRNLFEZDVAW-ARSRFYASSA-N
SMILES:C(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@H](O)CC1=O
Synonyms:
  • (-)-Prostaglandin E<sub>2</sub>
  • (11alpha,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
  • (15S)-Prostaglandin E2
  • (15S)-Prostaglandin E<sub>2</sub>
  • (5E,13E)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
  • (5Z,11alpha,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
  • (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oate
  • (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
  • (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate
  • 11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (5Z,11α,13E,15S)
  • See more synonyms
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