CAS 364-98-7: Diazoxide
Description:Diazoxide is a pharmaceutical compound primarily used as an antihypertensive agent and in the management of hypoglycemia. It is classified as a thiazide derivative and functions by relaxing vascular smooth muscle, leading to vasodilation and a subsequent decrease in blood pressure. The chemical structure of diazoxide includes a diazine ring, which contributes to its pharmacological properties. It is typically administered orally and has a relatively long half-life, allowing for sustained effects. Diazoxide is also known for its ability to inhibit insulin secretion from the pancreas, making it useful in specific clinical scenarios, such as in patients with insulinoma or other conditions associated with excessive insulin production. The compound is generally well-tolerated, but it may cause side effects such as fluid retention, tachycardia, and hyperglycemia. Due to its potent effects, diazoxide is usually prescribed under careful medical supervision, particularly in patients with cardiovascular issues. Its CAS number, 364-98-7, is used for identification in chemical databases and regulatory contexts.
Formula:C8H7ClN2O2S
InChI:InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
InChI key:InChIKey=GDLBFKVLRPITMI-UHFFFAOYSA-N
SMILES:O=S1(=O)N=C(NC2=CC=C(Cl)C=C21)C
- Synonyms:
- 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
- 3-Methyl-7-chloro-1,2,4-benzothiadiazine 1,1-dioxide
- 4H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
- 7-Chloro-3-Methyl-1Lambda~4~,2,4-Benzothiadiazin-1-Ol 1-Oxide
- 7-Chloro-3-methyl-2H-benzo[1,2,4]thiadiazine 1,1-dioxide
- 7-Chloro-3-methyl-4H-benzo[1,2,4]thiadiazine 1,1-dioxide
- 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- 7-chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide
- Diazoxid
- Diazoxido
- See more synonyms
- Dizoxide
- Eudemine injection
- Hyperstat
- Hypertonalum
- Mutabase
- Nsc 64198
- Nsc 76130
- Proglicem
- Proglycem
- Sch 6783
- Srg 95213
- Diazoxide