CAS 364782-34-3: Cinacalcet hydrochloride
Description:Cinacalcet hydrochloride is a synthetic compound primarily used as a medication to manage secondary hyperparathyroidism in patients with chronic kidney disease and to treat hypercalcemia in patients with parathyroid carcinoma. It functions as a calcimimetic agent, which means it enhances the sensitivity of calcium-sensing receptors on parathyroid cells, leading to decreased parathyroid hormone (PTH) secretion and subsequently lowering serum calcium levels. The substance is typically administered orally and is characterized by its white to off-white crystalline powder form. Its solubility profile indicates that it is soluble in water and methanol, which facilitates its absorption in the gastrointestinal tract. The molecular formula of cinacalcet hydrochloride reflects its complex structure, which includes multiple functional groups that contribute to its pharmacological activity. As with many medications, it is essential to monitor for potential side effects, including nausea, vomiting, and hypocalcemia, during treatment. Overall, cinacalcet hydrochloride plays a significant role in managing calcium homeostasis in specific patient populations.
Formula:C22H22F3N·ClH
InChI:InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1
InChI key:InChIKey=QANQWUQOEJZMLL-PKLMIRHRSA-N
SMILES:Cl.FC(F)(F)C=1C=CC=C(C1)CCCNC(C2=CC=CC=3C=CC=CC32)C
- Synonyms:
- 1-Naphthalenemethanamine, α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)-
- 1-Naphthalenemethanamine, α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, hydrochloride, (αR)-
- AMG 073 HCl
- Cinacalcet HCl
- Krn 1493
- Mimpara
- N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
- Regpara
- Sensipar
- [(1R)-1-(Naphthalen-1-yl)ethyl]([3-[3-(trifluoromethyl)phenyl]propyl])amine hydrochloride
- See more synonyms
- Cinacalcet hydrochloride