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Cinacalcet hydrochloride

CAS 364782-34-3: Cinacalcet hydrochloride

Description:Cinacalcet hydrochloride is a synthetic compound primarily used as a medication to manage secondary hyperparathyroidism in patients with chronic kidney disease and to treat hypercalcemia in patients with parathyroid carcinoma. It functions as a calcimimetic agent, which means it enhances the sensitivity of calcium-sensing receptors on parathyroid cells, leading to decreased parathyroid hormone (PTH) secretion and subsequently lowering serum calcium levels. The substance is typically administered orally and is characterized by its white to off-white crystalline powder form. Its solubility profile indicates that it is soluble in water and methanol, which facilitates its absorption in the gastrointestinal tract. The molecular formula of cinacalcet hydrochloride reflects its complex structure, which includes multiple functional groups that contribute to its pharmacological activity. As with many medications, it is essential to monitor for potential side effects, including nausea, vomiting, and hypocalcemia, during treatment. Overall, cinacalcet hydrochloride plays a significant role in managing calcium homeostasis in specific patient populations.

Formula:C22H22F3N·ClH

InChI:InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m1./s1

InChI key:InChIKey=QANQWUQOEJZMLL-PKLMIRHRSA-N

SMILES:Cl.FC(F)(F)C=1C=CC=C(C1)CCCNC(C2=CC=CC=3C=CC=CC32)C

  • Synonyms:
  • 1-Naphthalenemethanamine, α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, hydrochloride (1:1), (αR)-
  • 1-Naphthalenemethanamine, α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-, hydrochloride, (αR)-
  • AMG 073 HCl
  • Cinacalcet HCl
  • Krn 1493
  • Mimpara
  • N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride
  • Regpara
  • Sensipar
  • [(1R)-1-(Naphthalen-1-yl)ethyl]([3-[3-(trifluoromethyl)phenyl]propyl])amine hydrochloride
  • See more synonyms
  • Cinacalcet hydrochloride
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Found 12 products.

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Cinacalcet Hydrochloride

CAS:364782-34-3

Ref: 3B-C3833

1g208.00 €
Estimated delivery in United States, on Thursday 10 Apr 2025
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Cinacalcet Hydrochloride (N-[(1R)-1-(Naphthalen-1-yl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride)

CAS:364782-34-3

Ref: 45-1133977

250mg684.00 €
Estimated delivery in United States, on Wednesday 16 Apr 2025
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Ref: IN-DA00I787

1g130.00 €
5g281.00 €
25gTo inquire
100mg57.00 €
250mg68.00 €
Estimated delivery in United States, on Thursday 17 Apr 2025
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Cinacalcet hydrochloride

CAS:364782-34-3

Ref: 54-PC301203

1g89.00 €
5g297.00 €
25g1,037.00 €
250mg42.00 €
Estimated delivery in United States, on Monday 21 Apr 2025
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Cinacalcet HCl

CAS:364782-34-3

Ref: 4Z-C-401

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Monday 21 Apr 2025
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Cinacalcet hydrochloride

CAS:364782-34-3

Ref: 54-BUP15696

1g628.00 €
50mg130.00 €
100mg225.00 €
200mg288.00 €
500mg471.00 €
Estimated delivery in United States, on Monday 21 Apr 2025
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Cinacalcet Hydrochloride

Controlled Product
CAS:364782-34-3

Ref: 86-MM3370.00

100mg1,141.00 €
Estimated delivery in United States, on Tuesday 22 Apr 2025
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Cinacalcet hydrochloride

CAS:364782-34-3

Ref: TM-T2406

10mg50.00 €
25mg70.00 €
50mg88.00 €
100mg144.00 €
200mg185.00 €
500mg309.00 €
1mL*10mM (DMSO)52.00 €
Estimated delivery in United States, on Thursday 24 Apr 2025
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Ref: 10-F079280

1g120.00 €
5gTo inquire
25gTo inquire
Estimated delivery in United States, on Tuesday 29 Apr 2025
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Cinacalcet Hydrochloride

Controlled Product
CAS:364782-34-3

Ref: TR-C441800

10mg117.00 €
50mg388.00 €
100mg711.00 €
Estimated delivery in United States, on Tuesday 29 Apr 2025
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Cinacalcet-d4 Hydrochloride

Controlled Product
CAS:364782-34-3

Ref: TR-C441803

10mg1,056.00 €
25mg2,005.00 €
2500µg296.00 €
Estimated delivery in United States, on Tuesday 29 Apr 2025
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N-[1-(R)-(-)-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]-1-aminopropane hydrochloride

CAS:364782-34-3

Ref: 3D-IN58180

1g189.00 €
2g263.00 €
500mg155.00 €
Estimated delivery in United States, on Monday 28 Apr 2025
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