CAS 36507-30-9: Carbamazepine 10,11-epoxide
Description:Carbamazepine 10,11-epoxide is a pharmacologically active metabolite of carbamazepine, primarily known for its role in the treatment of epilepsy and bipolar disorder. This compound is characterized by its epoxide functional group, which contributes to its reactivity and biological activity. It typically appears as a white to off-white solid and is soluble in organic solvents. The molecular structure includes a dibenzazepine core, which is essential for its therapeutic effects. The compound exhibits anticonvulsant properties and is believed to modulate sodium channels, thereby stabilizing neuronal membranes. Additionally, it has been studied for its potential role in drug interactions and toxicity, particularly in relation to its metabolic pathways. Due to its epoxide nature, it can also participate in further chemical reactions, which may influence its pharmacokinetics and pharmacodynamics. As with many pharmaceuticals, the safety profile and side effects are important considerations in its clinical use. Overall, Carbamazepine 10,11-epoxide is a significant compound in neuropharmacology, contributing to the efficacy of carbamazepine therapy.
Formula:C15H12N2O2
InChI:InChI=1S/C15H12N2O2/c16-15(18)17-11-7-3-1-5-9(11)13-14(19-13)10-6-2-4-8-12(10)17/h1-8,13-14H,(H2,16,18)
InChI key:InChIKey=ZRWWEEVEIOGMMT-UHFFFAOYSA-N
SMILES:O=C(N)N1C=2C=CC=CC2C3OC3C=4C=CC=CC41
- Synonyms:
- 10,11-Dihydro-10,11-epoxycarbamazepine
- 10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide 10,11-epoxide
- 10,11-Epoxycarbamazepine
- 1a,10b-Dihydro-6H-dibenz(b,f)oxiren(d)azepine-6-carboxamide
- 1a,10b-Dihydro-6H-dibenz[b,f]oxireno[d]azepine-6-carboxamide
- 1a,10b-dihydro-6H-dibenzo[b,f]oxireno[d]azepine-6-carboxamide
- 6H-Dibenz(b,f)oxiren(d)azepine-6-carboxamide, 1a,10b-dihydro-
- 6H-Dibenz[b,f]oxireno[d]azepine-6-carboxamide, 1a,10b-dihydro-
- Brn 1219988
- Carbamazepine 10,11-oxide
- See more synonyms
- Carbamazepine epoxide
- Carbamazepine-10,11-trans-dihydrodiol
- Gp 49-023
- Carbamazepine 10,11-epoxide
- Carbamazepine-10,11-epoxide
- Carbamazepine 10,11-epoxide