CAS 366-77-8

3-(4-Fluorobenzoyl)propionic acid

Description:

3-(4-Fluorobenzoyl)propionic acid, with the CAS number 366-77-8, is an organic compound characterized by its propionic acid backbone substituted with a 4-fluorobenzoyl group. This compound typically appears as a white to off-white crystalline solid. It is known for its moderate solubility in polar solvents such as water and alcohols, while being less soluble in non-polar solvents. The presence of the fluorine atom in the aromatic ring can influence its chemical reactivity and biological activity, often enhancing lipophilicity and altering interaction with biological targets. The carboxylic acid functional group contributes to its acidity and potential for forming salts and esters. 3-(4-Fluorobenzoyl)propionic acid may be utilized in various applications, including pharmaceuticals and as an intermediate in organic synthesis. Its properties make it a subject of interest in medicinal chemistry, particularly in the development of compounds with specific biological activities. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₁₀H₉FO₃

InChI: InChI=1S/C10H9FO3/c11-8-3-1-7(2-4-8)9(12)5-6-10(13)14/h1-4H,5-6H2,(H,13,14)

InChI key: InChIKey=WUYWHIAAQYQKPP-UHFFFAOYSA-N

SMILES: C(CCC(O)=O)(=O)C1=CC=C(F)C=C1

Synonyms:

• 3-(4-Fluorobenzoyl)propanoic acid
• 3-(p-Fluorobenzoyl)propionic acid
• 4-(4-Fluorophenyl)-4-Oxobutanoic Acid
• 4-(4-Fluorophenyl)-4-oxobutyric acid
• 4-Fluoro-γ-oxobenzenebutanoic acid
• 4-Fluorobenzoylpropionic acid
• 4-Oxo-4-(p-fluorophenyl)butyric acid
• Ba 2833
• Benzenebutanoic acid, 4-fluoro-γ-oxo-
• Haloperidol metabolite III
• NSC 408180
• Propionic acid, 3-(p-fluorobenzoyl)-
• β-(4-Fluorobenzoyl)propionic acid
• β-(p-Fluorobenzoyl)propionic acid

3-(4-Fluorobenzoyl)propionic Acid

CAS: 366-77-8

Formula: C₁₀H₉FO₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 196.18

Ref: 3B-F0379

3-(4-Fluorobenzoyl)propionic acid, 97%

CAS: 366-77-8

7-Fluoro-1-tetralone was prepared from 3-(4-fluorobenzoyl)-propionic acid by Wolff-Kishner reduction followed by ring closure with polyphosphoric acid and other substituted 1-tetralones where commercially available. Reduction of 3-(4-fluorobenzoyl)propionic acid with an excess of tert-butylamine bor

Formula: C₁₀H₉FO₃

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White to cream

Molecular weight: 196.18

Ref: 02-A13755

3-(4-Fluorobenzoyl)-propionic acid

CAS: 366-77-8

Color and Shape: Neat

Ref: LP-FPA-1879-FA-10

3-(4-Fluorobenzoyl)propionic acid

CAS: 366-77-8

Formula: C₁₀H₉FO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 196.1751

Ref: IN-DA003I4B

4-(4-Fluorophenyl)-4-oxobutanoic acid

CAS: 366-77-8

4-(4-Fluorophenyl)-4-oxobutanoic acid

Purity: 98%

Color and Shape: White Powder

Molecular weight: 196.18g/mol

Ref: 54-PC3635

3-(4-Fluorobenzoyl)-propionic acid, 1mg/ml in Methanol

CAS: 366-77-8

Color and Shape: Single Solution

Ref: LP-FPA-1879-FA-1LM

3-(4-Fluorobenzoyl)propionic acid

CAS: 366-77-8

Formula: C₁₀H₉FO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 196.177

Ref: 10-F317872

4-(4-Fluorophenyl)-4-oxobutanoic Acid

Controlled Product

CAS: 366-77-8

Formula: C₁₀H₉FO₃

Color and Shape: Yellow To Orange

Molecular weight: 196.17

Ref: TR-F632283

3-(4-Fluorobenzoyl)propionic acid

CAS: 366-77-8

3-(4-Fluorobenzoyl)propionic acid (3FBP) is a novel, orally active dopamine D4 receptor agonist. 3FBP binds to the D4 receptor with high affinity and has been shown to have potent antinociceptive effects in CD-1 mice. The compound has also been shown to be effective in reducing locomotor activity in rats, as well as inducing motor impairment and catalepsy in mice. 3FBP does not produce any significant changes in striatal dopamine levels, suggesting that it may have a different mechanism of action than traditional dopaminergic drugs.

Formula: C₁₀H₉FO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 196.18 g/mol

Ref: 3D-FF10688