CAS 366789-02-8: Rivaroxaban

Description: Rivaroxaban is an oral anticoagulant medication primarily used for the prevention and treatment of thromboembolic disorders, such as deep vein thrombosis and pulmonary embolism. It functions as a direct factor Xa inhibitor, which disrupts the coagulation cascade and reduces the formation of blood clots. Rivaroxaban is characterized by its high bioavailability and predictable pharmacokinetics, allowing for fixed dosing without the need for routine monitoring of coagulation parameters. The substance is typically administered in tablet form and is absorbed rapidly, with peak plasma concentrations occurring within a few hours post-ingestion. It is metabolized primarily in the liver through cytochrome P450 enzymes and is excreted via both renal and fecal pathways. Common side effects may include bleeding complications, which necessitate caution in patients with certain risk factors. Rivaroxaban's efficacy and safety profile have made it a widely used option in anticoagulation therapy, although it is contraindicated in patients with active bleeding or severe renal impairment.

Formula: C₁₉H₁₈ClN₃O₅S

InChI: InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1

InChI key: InChIKey=KGFYHTZWPPHNLQ-AWEZNQCLSA-N

SMILES: O=C1OC(CNC(=O)C=2SC(Cl)=CC2)CN1C3=CC=C(C=C3)N4C(=O)COCC4

Synonyms:

• (S)-Rivaroxaban
• 2-Thiophenecarboxamide, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-
• 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)-1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamide
• 5-Chloro-N-([(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl]-methyl)-2-thiophenecarboxamide
• 5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
• 5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide
• 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]oxazolidin-5-yl]methyl]thiophene-2-carboxamide
• Bay 59-7939
• Rivaroxaban intermediates
• Rivaroxban
• Xarelto
• Rivaroxaban

Rivaroxaban CRS

CAS: 366789-02-8

Rivaroxaban

CAS: 366789-02-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₁₉H₁₈ClN₃O₅S
• Color and Shape: White Powder
• Molecular weight: 435.06557

5-Chloro-N-[[(S)-3-(4-(3-oxomorpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]-thiophene-2-carboxamide

CAS: 366789-02-8

• Formula: C₁₉H₁₈ClN₃O₅S
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 435.8813

Rivaroxaban

CAS: 366789-02-8

Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with …

• Formula: C₁₉H₁₈ClN₃O₅S
• Purity: 100% - 99.93%
• Color and Shape: Solid
• Molecular weight: 435.88

Rivaroxaban

CAS: 366789-02-8

• Purity: 99.5%
• Molecular weight: 435.88g/mol

Rivaroxaban

CAS: 366789-02-8

• Formula: C₁₉H₁₈ClN₃O₅S
• Purity: ≥ 98.0% (dried basis)
• Color and Shape: White to off-white powder
• Molecular weight: 435.88

Rivaroxaban

CAS: 366789-02-8

• Formula: C₁₉H₁₈ClN₃O₅S
• Color and Shape: White To Off-White Solid
• Molecular weight: 435.88

Rivaroxaban

CAS: 366789-02-8

• Purity: 99.69%
• Molecular weight: 435.88g/mol

Rivaroxaban

CAS: 366789-02-8

• Formula: C₁₉H₁₈ClN₃O₅S
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 435.88

Rivaroxaban, 98%

CAS: 366789-02-8

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Purity: 98%
• Color and Shape: White to off-white, Powder

Rivaroxaban

CAS: 366789-02-8

• Formula: C₁₉H₁₈ClN₃O₅S
• Color and Shape: Neat
• Molecular weight: 435.88

Rivaroxaban

CAS: 366789-02-8

Applications A novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor. References Ansell, …

• Formula: C₁₉H₁₈ClN₃O₅S
• Color and Shape: White To Beige
• Molecular weight: 435.88

Rivaroxaban - Bio-X ™

CAS: 366789-02-8

Rivaroxaban is a natural drug that is a direct factor Xa inhibitor. It has been …

• Formula: C₁₉H₁₈ClN₃O₅S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 435.88 g/mol

Rivaroxaban

CAS: 366789-02-8

Rivaroxaban is a natural drug that is a direct factor Xa inhibitor. It has been …

• Formula: C₁₉H₁₈ClN₃O₅S
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 435.88 g/mol