CAS 36724-68-2

(S)-(-)-N-(trifluoroacetyl)prolyl chlor-ide

Formula: C₇H₇ClF₃NO₂

InChI: InChI=1/C7H7ClF3NO2/c8-5(13)4-2-1-3-12(4)6(14)7(9,10)11/h4H,1-3H2/t4-/m0/s1

SMILES: C1C[C@@H](C(=O)Cl)N(C1)C(=O)C(F)(F)F

Synonyms:

• (S)-()-N-(Trifluoroacetyl)prolyl chloride
• 1-(trifluoroacetyl)-L-prolyl chloride

(2S)-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carbonyl chloride

CAS: 36724-68-2

Formula: C₇H₇ClF₃NO₂

Molecular weight: 229.5842

Ref: IN-DA003CF6

(S)-(-)-N-(Trifluoroacetyl)pyrrolidine-2-carbonyl chloride, 0.1M in methylene chloride

CAS: 36724-68-2

(S)-(-)-N-(Trifluoroacetyl)Prolyl Chloride is a chemical compound that has been shown to inhibit the ion channel TRPC2 in human heart cells. The compound is a prodrug and is metabolized by esterases to the active form, pentafluoroproprionyl chloride. This active form then inhibits the sodium-potassium pump, which leads to an increase in intracellular calcium and cell death. (S)-(-)-N-(Trifluoroacetyl)Prolyl Chloride may be used as a potential treatment for congestive heart failure. It has also been shown to be effective in treating methamphetamine dependence, with a single dose of 50 mg being sufficient to suppress withdrawal symptoms for up to 12 hours. (S)-(-)-N-(Trifluoroacetyl)Prolyl Chloride is not detectable in urine samples after 24 hours and has no detectable effect on liver function tests

Formula: C₇H₇ClF₃NO₂

Purity: Min. 95%

Molecular weight: 229.58 g/mol

Ref: 3D-FT86906