CAS 36791-04-5
:Ribavirin
Description:
Ribavirin is an antiviral medication primarily used to treat viral infections, particularly hepatitis C and respiratory syncytial virus (RSV). It is classified as a nucleoside analog, which means it mimics the building blocks of RNA and DNA, thereby interfering with viral replication. The chemical formula of ribavirin is C₁₁H₁₅N₄O₅P, and it features a guanosine-like structure that allows it to inhibit viral RNA synthesis. Ribavirin is often administered in combination with other antiviral agents to enhance its efficacy. The substance is typically presented as a white to off-white crystalline powder, soluble in water and slightly soluble in alcohol. Its mechanism of action involves the inhibition of viral RNA polymerase and the induction of mutagenesis in viral genomes, leading to the production of defective viral particles. While effective, ribavirin can have side effects, including hemolytic anemia and teratogenic effects, necessitating careful monitoring during treatment. Due to its specific action against RNA viruses, ribavirin remains a critical component in the management of certain viral infections.
Formula:C8H12N4O5
InChI:InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChI key:InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2N=C(C(N)=O)N=C2
Synonyms:- 1-Beta-D-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide
- 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
- 1-pentofuranosyl-1H-1,2,4-triazole-3-carboxamide
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazole-3-carboxamide
- 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
- 1-β-D-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
- 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
- 1H-1,2,4-Triazole-3-carboxamide, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 1H-1,2,4-Triazole-3-carboxamide, 1-β-D-ribofuranosyl-
- Biopolymers
- Copegus
- Cotronak
- Ebp 954
- Icn 1229
- Meduna
- MegaRibavirin
- Nsc 163039
- Ravanex
- Rebetol
- Ribamide
- Ribamidil
- Ribasphere
- Ribavarin
- Rtca
- Tribavirin
- Vilona
- Viramid
- Virazid
- Virazole
- Virin
- Virizadole
- See more synonyms
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Ribavirin
CAS:Formula:C8H12N4O5Purity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:244.21RIBAVIRIN CRS
CAS:RIBAVIRIN CRSFormula:C8H12N4O5Color and Shape:Added ModifiedMolecular weight:244.2047Ribavirin
CAS:RibavirinFormula:C8H12N4O5Purity:99.9%Color and Shape:White SolidMolecular weight:244.08077Ribavirin
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C8H12N4O5Color and Shape:White Crystalline PowderMolecular weight:244.21 g/molRibavirin
CAS:Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.Formula:C8H12N4O5Purity:99.09% - 99.83%Color and Shape:SolidMolecular weight:244.201-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
CAS:Formula:C8H12N4O5Purity:98%Color and Shape:SolidMolecular weight:244.2047Ribavirin
CAS:RibavirinFormula:C8H12N4O5Purity:99.97% (Typical Value in Batch COA)Color and Shape:Solid-PowderMolecular weight:244.20468Ribavirin
CAS:Formula:C8H12N4O5Purity:≥ 98.0% (dried basis)Color and Shape:White to off-white powderMolecular weight:244.20Ribavirin 100 µg/mL in Acetonitrile:Methanol
CAS:Controlled ProductFormula:C8H12N4O5Color and Shape:Single SolutionMolecular weight:244.20Ribavirin
CAS:Controlled ProductApplications Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.
References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)Formula:C8H12N4O5Color and Shape:NeatMolecular weight:244.2Ribavirin
CAS:Controlled ProductRibavirin is a guanosine nucleoside analog with broad-spectrum antiviral properties. Ribavirin gets phosphorylated to ribavirin triphosphate in cells and competes with natural nucleotides for incorporation in a nascent RNA chain, thus interfering with RNA synthesis by inhibiting viral RNA polymerases. Ribavirin is also an inhibitor of inosinate dehydrogenase (IMP), which is involved in the biosynthesis of GTP.
Formula:C8H12N4O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:244.2 g/molRibavirin
CAS:1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamideFormula:C8H12N4O5Purity:98%Molecular weight:244.2
