CAS 36791-04-5

Ribavirin

Description:

Ribavirin is an antiviral medication primarily used to treat viral infections, particularly hepatitis C and respiratory syncytial virus (RSV). It is classified as a nucleoside analog, which means it mimics the building blocks of RNA and DNA, thereby interfering with viral replication. The chemical formula of ribavirin is C₁₁H₁₅N₄O₅P, and it features a guanosine-like structure that allows it to inhibit viral RNA synthesis. Ribavirin is often administered in combination with other antiviral agents to enhance its efficacy. The substance is typically presented as a white to off-white crystalline powder, soluble in water and slightly soluble in alcohol. Its mechanism of action involves the inhibition of viral RNA polymerase and the induction of mutagenesis in viral genomes, leading to the production of defective viral particles. While effective, ribavirin can have side effects, including hemolytic anemia and teratogenic effects, necessitating careful monitoring during treatment. Due to its specific action against RNA viruses, ribavirin remains a critical component in the management of certain viral infections.

Formula: C₈H₁₂N₄O₅

InChI: InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1

InChI key: InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2N=C(C(N)=O)N=C2

Synonyms:

• 1-Beta-D-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide
• 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
• 1-pentofuranosyl-1H-1,2,4-triazole-3-carboxamide
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1,2,4-triazole-3-carboxamide
• 1-β-<span class="text-smallcaps">D</span>-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
• 1-β-D-Ribofuranosyl-1,2,4-triazol-3-carboxyamide
• 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
• 1H-1,2,4-Triazole-3-carboxamide, 1-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• 1H-1,2,4-Triazole-3-carboxamide, 1-β-D-ribofuranosyl-
• Biopolymers
• Copegus
• Cotronak
• Ebp 954
• Icn 1229
• Meduna
• MegaRibavirin
• Nsc 163039
• Ravanex
• Rebetol
• Ribamide
• Ribamidil
• Ribasphere
• Ribavarin
• Rtca
• Tribavirin
• Vilona
• Viramid
• Virazid
• Virazole
• Virin
• Virizadole

Ribavirin

CAS: 36791-04-5

Formula: C₈H₁₂N₄O₅

Molecular weight: 244.21

Ref: ST-EA-CP-R81000

Ribavirin RS

CAS: 36791-04-5

Color and Shape: White Solid Crystalline Powder

Ref: 2K-1181700021

Ribavirin, Antibiotic for Culture Media Use Only

Controlled Product

CAS: 36791-04-5

Ribavirin is an antiviral agent used for the treatment of hepatitis C, respiratory syncytial virus infection and influenza. It is a monocarboxylic acid derived from vitamin B2. Ribavirin inhibits viral replication by interfering with the function of RNA polymerase. Ribavirin also has immunosuppressive properties that can be useful in treating autoimmune disorders such as systemic lupus erythematosus and it has been approved by the FDA for treatment of chronic hepatitis C virus (HCV) genotype 1 infection with compensated liver disease or decompensated liver disease with or without HCV genotype 3 infection. The antiviral activity of ribavirin against other viruses, including HIV-1, herpes simplex virus type 2, varicella zoster virus, cytomegalovirus, respiratory syncytial virus, influenza A and B viruses has been reported but not largely studied.

Formula: C₈H₁₂N₄O₅

Purity: Min. 97.0 Area-%

Molecular weight: 244.20 g/mol

Ref: 3D-Q-201670