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CAS 370-81-0

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Cuprizone

Description:
Cuprizone, with the CAS number 370-81-0, is a synthetic compound primarily used in biochemical research, particularly in studies related to copper metabolism and neurodegenerative diseases. It is a chelating agent that selectively binds copper ions, thereby reducing their availability in biological systems. Cuprizone is often utilized in experimental models to induce demyelination in the central nervous system, mimicking conditions such as multiple sclerosis. The compound is typically characterized by its ability to disrupt copper homeostasis, leading to cellular stress and neurotoxicity. In terms of physical properties, cuprizone is a white to off-white crystalline solid that is soluble in organic solvents but has limited solubility in water. Its mechanism of action involves the inhibition of copper-dependent enzymes, which can result in oxidative stress and neuronal damage. Due to its specific interactions with copper, cuprizone serves as a valuable tool in understanding the role of metal ions in neurobiology and the pathophysiology of various neurological disorders.
Formula:C14H22N4O2
InChI:InChI=1/C14H22N4O2/c19-13(17-15-11-7-3-1-4-8-11)14(20)18-16-12-9-5-2-6-10-12/h1-10H2,(H,17,19)(H,18,20)
InChI key:InChIKey=DSRJIHMZAQEUJV-UHFFFAOYSA-N
SMILES:N(NC(C(NN=C1CCCCC1)=O)=O)=C2CCCCC2
Synonyms:
  • Bis(1,5-cyclohexanone) oxal dihydrazone
  • Bis(cyclohexanone)oxaldihydrazone
  • Biscyclohexanone oxalyldihydrazone
  • Chromium(III) ionophore III
  • Cuprizon
  • Cuprizon 1
  • Cuprizon l
  • Cuprizone
  • Ethanedioic acid, 1,2-bis(2-cyclohexylidenehydrazide)
  • Ethanedioic acid, bis(cyclohexylidenehydrazide)
  • See more synonyms
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