CAS 372196-67-3: Benzenesulfonic acid,2-methyl-5-nitro-,2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide

Description: Benzenesulfonic acid, 2-methyl-5-nitro-, 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide, identified by CAS number 372196-67-3, is a complex organic compound characterized by its multifunctional structure. It features a benzenesulfonic acid moiety, which contributes to its acidic properties and potential solubility in polar solvents. The presence of a nitro group indicates potential reactivity and the ability to participate in electrophilic substitution reactions. The imidazo[1,2-a]pyridine component introduces heterocyclic characteristics, which can influence the compound's biological activity and interaction with biological targets. Additionally, the hydrazide functional group suggests potential for forming hydrazones, which may be relevant in medicinal chemistry. Overall, this compound's unique structural features may confer specific pharmacological properties, making it of interest in drug development and research applications. Its stability, solubility, and reactivity would depend on the surrounding conditions and the presence of other functional groups in the environment.

Formula: C₁₆H₁₄BrN₅O₄S

Synonyms:

• Benzenesulfonicacid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide(9CI)
• Pik 75
• N'-[(1Z)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylidene]-N,2-dimethyl-5-nitrobenzenesulfonohydrazide
• Benzenesulfonic acid, 2-methyl-5-nitro-, [(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]methylhydrazide

2-Methyl-5-nitro-1-benzenesulfonic acid 2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide

CAS: 372196-67-3

• Formula: C₁₆H₁₄BrN₅O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 452.2825

PIK-75

CAS: 372196-67-3

• Purity: 98%
• Molecular weight: 452.28g/mol

PIK-75

CAS: 372196-67-3

• Purity: >99%
• Color and Shape: Solid
• Molecular weight: 452.28g/mol

PIK-75

CAS: 372196-67-3

PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).

• Formula: C₁₆H₁₄BrN₅O₄S
• Purity: 100% - 99.88%
• Color and Shape: Solid
• Molecular weight: 452.28

PIK-75

CAS: 372196-67-3

PIK-75

CAS: 372196-67-3

Applications PIK-75 is a p110α inhibitor, isoform-specific mutants at Ser773, and also potently inhibits DNA-PK. …

• Formula: C₁₆H₁₄BrN₅O₄S
• Color and Shape: Light Yellow To Yellow
• Molecular weight: 452.28

PIK-75

CAS: 372196-67-3

PIK-75 is a novel small molecule that binds to the MCL-1 protein and inhibits its …

• Formula: C₁₆H₁₄BrN₅O₄S
• Purity: Min. 95%
• Molecular weight: 452.28 g/mol