CAS 37248-47-8

Validamycin A

Description:

Validamycin A is a naturally occurring antibiotic and fungicide, primarily derived from the fermentation of the bacterium Streptomyces hygroscopicus. It is characterized by its complex structure, which includes a sugar moiety and a cyclic peptide component, contributing to its biological activity. Validamycin A exhibits strong antifungal properties, particularly against various plant pathogens, making it valuable in agricultural applications for crop protection. Its mechanism of action involves the inhibition of chitin synthesis in fungal cell walls, which is crucial for their growth and survival. Additionally, Validamycin A has been studied for its potential use in controlling certain bacterial infections and as a biopesticide due to its low toxicity to non-target organisms. The compound is soluble in water and exhibits stability under various environmental conditions, which enhances its utility in agricultural formulations. Overall, Validamycin A represents a significant advancement in the development of environmentally friendly pest control agents.

Formula: C₂₀H₃₅NO₁₃

InChI: InChI=1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11-,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1

InChI key: InChIKey=JARYYMUOCXVXNK-CSLFJTBJSA-N

SMILES: O([C@@H]1[C@@H](CO)C[C@H](N[C@H]2C=C(CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O

Synonyms:

• ((1S,4R,5S,6S)-4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-
• (1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside
• (1S,2S,3R,4R,6S)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(4S,5R,6R)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside
• (1S-(1a,4a,5B,6a))-1,5,6-Trideoxy-3-O-B-D-glucopyranosyl-5-
• (1S-(1alpha,4alpha,5beta,6alpha))-1,5,6-trideoxy-4-O-beta-D-
• (hydroxymethyl)-1-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-
• (hydroxymethyl)-2-cyclohexen-1-yl)amino)-D-chiro-inositol
• 1,5,6-Trideoxy-4-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-<smallcap>D</span>-chiro-inositol
• 1L-(1,3,4/2,6)-2,3-Dihydroxy-6-hydromethyl-4-((1S,4R,5S,6S)-
• 1L-(1,3,4/2,6)-2,3-Dihydroxy-6-hydroxymethyl-4-
• 2,3-Dihydroxy-6-(Hydroxymethyl)-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Cyclohexyl Hexopyranoside
• 4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 1,5,6-trideoxy-4-O-β-<smallcap>D</span>-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-
• <span class="text-smallcaps">D</smallcap>-chiro-Inositol, 1,5,6-trideoxy-4-O-β-<smallcap>D</span>-glucopyranosyl-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, [1S-(1α,4α,5β,6α)]-
• Cepex 10SL
• D-1,5,6-Trideoxy-3-O-beta-D-glucopyranosyl-5-
• Jinganmycin A
• Jinggang
• Jinggangmycin
• Jinggangmycin A
• Validacin
• Validamycin
• Validamycin A
• cyclohexen-1-yl)amino)-D-chiroinositol
• cyclohexen-1-yl)amino)-d-chiro-inositol
• enylamino)cyclohexyl beta-D-glucopyranoside
• glucopyranosyl-5-(hydroxymethyl)-1-((4,5,6-trihydroxy-3-
• D-chiro-Inositol, 1,5,6-trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-, [1S-(1α,4α,5β,6α)]-
• 1,5,6-Trideoxy-4-O-β-D-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-D-chiro-inositol

Validamycin

CAS: 37248-47-8

Formula: C₂₀H₃₅NO₁₃

Purity: %

Color and Shape: Solid

Molecular weight: 497.4908

Ref: IN-DA007A5W

Validamycin A

CAS: 37248-47-8

Formula: C₂₀H₃₅NO₁₃

Purity: ≥ 60.0%

Color and Shape: Off-white to light yellow powder

Molecular weight: 497.50

Ref: 7W-GA4672

Validamycin A

CAS: 37248-47-8

Validamycin A

Purity: ≥98%

Molecular weight: 497.49g/mol

Ref: 54-BUP21397

Validamycin A

CAS: 37248-47-8

Validamycin A is an antibiotic and fungicide that inhibits the alginate enzyme trehalase Rhizoctonia solani, reversible inhibitor of tyrosinase.

Formula: C₂₀H₃₅NO₁₃

Purity: 98.84%

Color and Shape: White Powder

Molecular weight: 497.49

Ref: TM-T38268

Validamycin A

CAS: 37248-47-8

Formula: C₂₀H₃₅NO₁₃

Molecular weight: 497.49

Ref: 4Z-V-046007

Validamycin A Sulfate salt (Technical grade)

CAS: 37248-47-8

Applications Validamycin A (>70%) Hydrochloride Salt is a metabolite of Validamycin A (>70%) (V943430) which is an antibiotic fungicide that inhibits trehalase activity in plants, insects, and fungi.

Formula: C₂₀H₃₅NO₁₃·xH₂SO₄

Purity: >70%

Color and Shape: Off-White To Light Brown

Molecular weight: 497.4908

Ref: TR-V943435

Validamycin A

CAS: 37248-47-8

Validamycin A is an antibiotic and fungicide with action as a trehalase inhibitor, disrupting carbohydrate metabolism in fungi and is used for controlling fungal diseases like sheath blight in rice and damping-off in cucumbers.

Formula: C₂₀H₃₅NO₁₃

Purity: Min. 92 Area-%

Color and Shape: White Powder

Molecular weight: 497.49 g/mol

Ref: 3D-AV59477

VALIDAMYCIN

CAS: 37248-47-8

Purity: 60+%

Molecular weight: 497.493988

Ref: 10-F826985

Validamycin A (>70%) Hydrochloride

CAS: 37248-47-8

Applications Validamycin A is an antibiotic fungicide that inhibits trehalase activity in plants, insects, and fungi.

Formula: C₂₀H₃₅NO₁₃·xHCl

Purity: >70%

Color and Shape: Neat

Molecular weight: 497.4908

Ref: TR-V943430