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CAS 37248-47-8

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Validamycin A

Description:
Validamycin A is a naturally occurring antibiotic and fungicide, primarily derived from the fermentation of the bacterium Streptomyces hygroscopicus. It is characterized by its complex structure, which includes a sugar moiety and a cyclic peptide component, contributing to its biological activity. Validamycin A exhibits strong antifungal properties, particularly against various plant pathogens, making it valuable in agricultural applications for crop protection. Its mechanism of action involves the inhibition of chitin synthesis in fungal cell walls, which is crucial for their growth and survival. Additionally, Validamycin A has been studied for its potential use in controlling certain bacterial infections and as a biopesticide due to its low toxicity to non-target organisms. The compound is soluble in water and exhibits stability under various environmental conditions, which enhances its utility in agricultural formulations. Overall, Validamycin A represents a significant advancement in the development of environmentally friendly pest control agents.
Formula:C20H35NO13
InChI:InChI=1S/C20H35NO13/c22-3-6-1-8(12(26)15(29)11(6)25)21-9-2-7(4-23)19(17(31)13(9)27)34-20-18(32)16(30)14(28)10(5-24)33-20/h1,7-32H,2-5H2/t7-,8+,9+,10-,11-,12+,13+,14-,15+,16+,17-,18-,19-,20+/m1/s1
InChI key:InChIKey=JARYYMUOCXVXNK-CSLFJTBJSA-N
SMILES:O([C@@H]1[C@@H](CO)C[C@H](N[C@H]2C=C(CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O
Synonyms:
  • ((1S,4R,5S,6S)-4,5,6-trihydroxy-3-hydroxymethylcyclohex-2-
  • (1R,2R,3S,4S,6R)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside
  • (1S,2S,3R,4R,6S)-2,3-dihydroxy-6-(hydroxymethyl)-4-{[(4S,5R,6R)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl beta-D-glucopyranoside
  • (1S-(1a,4a,5B,6a))-1,5,6-Trideoxy-3-O-B-D-glucopyranosyl-5-
  • (1S-(1alpha,4alpha,5beta,6alpha))-1,5,6-trideoxy-4-O-beta-D-
  • (hydroxymethyl)-1-((4,5,6-trihydroxy-3-(hydroxymethyl)-2-
  • (hydroxymethyl)-2-cyclohexen-1-yl)amino)-D-chiro-inositol
  • 1,5,6-Trideoxy-4-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-5-(hydroxymethyl)-1-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-<smallcap>D</span>-chiro-inositol
  • 1L-(1,3,4/2,6)-2,3-Dihydroxy-6-hydromethyl-4-((1S,4R,5S,6S)-
  • 1L-(1,3,4/2,6)-2,3-Dihydroxy-6-hydroxymethyl-4-
  • See more synonyms
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