CAS 3737-09-5: Disopyramide
Description:Disopyramide is a medication primarily used as an antiarrhythmic agent to treat certain types of irregular heartbeats, particularly ventricular arrhythmias. It belongs to the class of drugs known as sodium channel blockers, which work by inhibiting the influx of sodium ions during the cardiac action potential, thereby stabilizing the cardiac membrane and reducing excitability. Disopyramide is characterized by its chemical formula C20H24N2O, and it typically appears as a white to off-white crystalline powder. The substance is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water. Its pharmacological effects include negative inotropic action, which can decrease myocardial contractility, and it may also have anticholinergic properties, leading to side effects such as dry mouth and urinary retention. Disopyramide is administered orally and is subject to careful monitoring due to potential side effects and interactions with other medications. As with any antiarrhythmic, its use requires consideration of the patient's overall health and specific cardiac conditions.
Formula:C21H29N3O
InChI:InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
InChI key:InChIKey=UVTNFZQICZKOEM-UHFFFAOYSA-N
SMILES:O=C(N)C(C1=NC=CC=C1)(C=2C=CC=CC2)CCN(C(C)C)C(C)C
- Synonyms:
- (RS)-disopyramide
- 2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-
- 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-
- 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide
- Dicorantil
- Disopiramida
- Disopyramid
- Disopyramide
- H 3292
- Isorythm
- See more synonyms
- Lispine
- Ritmilen
- Ritmodan
- Sc 7031
- Searle 703
- dl-Disopyramide
- α-[2-(Diisopropylamino)ethyl]-α-phenyl-2-pyridineacetamide
- α-[2-[Bis(1-methylethyl)amino]ethyl]-α-phenyl-2-pyridineacetamide