CAS 3737-09-5
:Disopyramide
Description:
Disopyramide is a medication primarily used as an antiarrhythmic agent to treat certain types of irregular heartbeats, particularly ventricular arrhythmias. It belongs to the class of drugs known as sodium channel blockers, which work by inhibiting the influx of sodium ions during the cardiac action potential, thereby stabilizing the cardiac membrane and reducing excitability. Disopyramide is characterized by its chemical formula C20H24N2O, and it typically appears as a white to off-white crystalline powder. The substance is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water. Its pharmacological effects include negative inotropic action, which can decrease myocardial contractility, and it may also have anticholinergic properties, leading to side effects such as dry mouth and urinary retention. Disopyramide is administered orally and is subject to careful monitoring due to potential side effects and interactions with other medications. As with any antiarrhythmic, its use requires consideration of the patient's overall health and specific cardiac conditions.
Formula:C21H29N3O
InChI:InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25)
InChI key:InChIKey=UVTNFZQICZKOEM-UHFFFAOYSA-N
SMILES:C(CCN(C(C)C)C(C)C)(C(N)=O)(C1=CC=CC=C1)C2=CC=CC=N2
Synonyms:- (RS)-disopyramide
- 2-Pyridineacetamide, α-[2-(diisopropylamino)ethyl]-α-phenyl-
- 2-Pyridineacetamide, α-[2-[bis(1-methylethyl)amino]ethyl]-α-phenyl-
- 4-Diisopropylamino-2-phenyl-2-(2-pyridyl)butyramide
- Dicorantil
- Disopiramida
- Disopyramid
- Disopyramide
- H 3292
- Isorythm
- Lispine
- Ritmilen
- Ritmodan
- Sc 7031
- Searle 703
- dl-Disopyramide
- α-[2-(Diisopropylamino)ethyl]-α-phenyl-2-pyridineacetamide
- See more synonyms
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Found 15 products.
Disopyramide
CAS:Formula:C21H29N3OPurity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:339.48DISOPYRAMIDE CRS
CAS:<p>DISOPYRAMIDE CRS</p>Formula:C21H29N3OColor and Shape:White. Whitish. Powder.Molecular weight:339.4745α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide
CAS:Formula:C21H29N3OPurity:98%Color and Shape:SolidMolecular weight:339.4745Disopyramide
CAS:<p>Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.</p>Formula:C21H29N3OPurity:99.62%Color and Shape:SolidMolecular weight:339.47Disopyramide
CAS:Formula:C21H29N3OPurity:≥ 98.0%Color and Shape:White solid or powderMolecular weight:339.47Disopyramide
CAS:Controlled Product<p>Applications Antiarrhythmic (class IA). Sodium channel blocker.<br>References Adelstein, et al.: J. Med. Chem., 16, 309 (1973), Czeisler, J.L., et al.: J. Pharm. Sci., 74, 750 (1985), Taylor, E.H., et al.: Ann. Clin. Lab. Sci., 16, 289 (1986),<br></p>Formula:C21H29N3OColor and Shape:NeatMolecular weight:339.47Disopyramid
CAS:Controlled Product<p>a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide is a hydrogen bond donor. It has been shown to have cytotoxicity in vitro, with parameters that can be used for accurate prediction of descriptors. These descriptors are informative and insightful, which can be used for regression analyses and linear regression methods. The pharmacokinetic properties of a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide have been studied in humans and have shown linearity between dose and plasma concentration.</p>Formula:C21H29N3OColor and Shape:White PowderMolecular weight:339.47 g/mol
