CAS 37519-14-5

3-Hydroxyacetaminophen

Description:

3-Hydroxyacetaminophen, also known as paracetamol or acetaminophen, is a widely used analgesic and antipyretic agent. It is characterized by its ability to relieve pain and reduce fever, making it a common over-the-counter medication. The molecular structure features a hydroxyl group (-OH) and an acetaminophen moiety, which contribute to its pharmacological properties. This compound is typically administered orally and is well-absorbed in the gastrointestinal tract. It is metabolized primarily in the liver, where it undergoes conjugation to form non-toxic metabolites. 3-Hydroxyacetaminophen is generally considered safe when used at recommended doses, but overdose can lead to severe liver damage due to the accumulation of toxic metabolites. Its solubility in water and organic solvents allows for various formulations, including tablets, capsules, and liquid suspensions. Additionally, it has a relatively low potential for gastrointestinal irritation compared to non-steroidal anti-inflammatory drugs (NSAIDs), making it a preferred choice for many patients. Overall, 3-Hydroxyacetaminophen is an essential medication in pain management and fever reduction.

Formula: C₈H₉NO₃

InChI: InChI=1S/C8H9NO3/c1-5(10)9-6-2-3-7(11)8(12)4-6/h2-4,11-12H,1H3,(H,9,10)

InChI key: InChIKey=IPFBMHOMTSBTSU-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC(O)=C(O)C=C1

Synonyms:

• 3-Hydroxyacetaminophen
• 4-(Acetylamino)catechol
• 4-Acetylaminopyrocatechol
• Acetamide, N-(3,4-dihydroxyphenyl)-
• Acetanilide, 3′,4′-dihydroxy-
• N-(3,4-Dihydroxyphenyl)acetamide

3-Hydroxyacetaminophen

CAS: 37519-14-5

Formula: C₈H₉NO₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 167.1620

Ref: IN-DA00C6IK

Acetaminophen metabolite 3-hydroxy-acetaminophen

CAS: 37519-14-5

Acetaminophen metabolite 3-hydroxy-acetaminophen is an antioxidant and a non-toxic microsomal metabolite of acetaminophen, suitable for metabolic studies.

Formula: C₈H₉NO₃

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 167.16

Ref: TM-T19175

3-Hydroxyacetaminophen

CAS: 37519-14-5

Formula: C₈H₉NO₃

Molecular weight: 167.16

Ref: 4Z-A-0235

3-Hydroxyacetaminophen-d3

CAS: 37519-14-5

Formula: C₈H₆D₃NO₃

Molecular weight: 170.18

Ref: 4Z-A-022

3-Hydroxyacetaminophen

Controlled Product

CAS: 37519-14-5

Applications 3-Hydroxyacetaminophen is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).
References (1) Chen, C., et al.: J. Biol. Chem., 283, 4543 (2008)(2) Reith, D., et al.: Clin. Exper. Pharmacol. Physiol., 36, 35 (2009) (3) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)

Formula: C₈H₉NO₃

Color and Shape: Neat

Molecular weight: 167.16

Ref: TR-H714750

N-(3,4-Dihydroxyphenyl)acetamide

CAS: 37519-14-5

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 167.16400146484375

Ref: 10-F384954

3-Hydroxyacetaminophen

CAS: 37519-14-5

Formula: C₈H₉NO₃

Molecular weight: 167.16

Ref: ST-EA-CP-A7015