CAS 3778-73-2: Ifosfamide

Description: Ifosfamide is a synthetic alkylating agent primarily used in chemotherapy for treating various cancers, including testicular cancer, sarcomas, and lymphomas. It is a prodrug, meaning it requires metabolic activation in the liver to exert its therapeutic effects. Ifosfamide is structurally related to cyclophosphamide and functions by forming DNA cross-links, which inhibit DNA replication and transcription, ultimately leading to cell death. The compound is typically administered intravenously and is known for its potential side effects, which can include myelosuppression, neurotoxicity, and bladder toxicity, necessitating the use of protective agents like mesna to mitigate these risks. Ifosfamide is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, and it has a relatively high solubility in water. Its pharmacokinetics involve rapid distribution and metabolism, with a half-life that can vary based on individual patient factors. Overall, Ifosfamide remains an important agent in oncological therapy, despite its associated toxicities.

Formula: C₇H₁₅Cl₂N₂O₂P

InChI: InChI=1S/C7H15Cl2N2O2P/c8-2-4-10-14(12)11(6-3-9)5-1-7-13-14/h1-7H2,(H,10,12)

InChI key: InChIKey=HOMGKSMUEGBAAB-UHFFFAOYSA-N

SMILES: O=P1(OCCCN1CCCl)NCCCl

Synonyms:

• (2-Chloro-ethyl)-[3-(2-chloro-ethyl)-2-oxo-2λ*5*-[1,3,2]oxazaphosphinan-2-yl]-amine
• 1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
• 2,3-N,N(sup 1)-Bis(2-chloroethyl)diamido-1,3,2-oxazaphosphoridinoxy-
• 2H-1,3,2-Oxazaphosphorin-2-amine, N,3-bis(2-chloroethyl)tetrahydro-, 2-oxide
• 2H-1,3,2-Oxazaphosphorine, 3-(2-chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-, 2-oxide
• 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxaazaphosphorin 2-oxide
• 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorin 2-oxide
• 3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
• 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide
• 3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
• A 4942
• Asta Z 4942
• Cyfos
• Holoxan
• Holoxan 1000
• Ifex
• Ifomide
• Ifosfamid
• Ifosfamida
• Ifosfomide
• Ifosphamide
• Iphosphamid
• Iphosphamid(e)
• Iphosphamide
• Isoendoxan
• Isofosfamide
• Isophosphamide
• Mitoxana
• Mjf 9325
• N,3-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
• N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylene phosphoric acid ester diamide
• N-(2-Chloroethyl)-N'-(2-chloroethyl)-N',O-propylenephosphoric acid diamide
• Naxamide
• Nsc 109724
• Z 4942
• Z4942
• Ifosfamide

Ifosfamide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: >95.0%(GC)(T)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 261.08

Ifosfamide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: 100.0%
• Color and Shape: White To Off-White
• Molecular weight: 260.02482

Ifosfamide CRS

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Color and Shape: Powder
• Molecular weight: 261.086

Ifosfamide

CAS: 3778-73-2

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₇H₁₅Cl₂N₂O₂P
• Color and Shape: White Crystalline Powder
• Molecular weight: 260.02482

3-(2-Chloroethyl)-2-(2-chloroethylamino)tetrahydro-2H-1,3,2-oxaazaphosphorin 2-oxide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 261.086

Ifosfamide

CAS: 3778-73-2

Ifosfamide (NSC-109724), a prodrug, is a cyclophosphamide analog with antineoplastic action by DNA alkylation and …

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: 100% - ≥95%
• Color and Shape: Solid
• Molecular weight: 261.09

Ifosfamide

CAS: 3778-73-2

• Purity: 99.86%
• Molecular weight: 261.09g/mol

Ifosfamide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Molecular weight: 261.08

Ifosfamide

CAS: 3778-73-2

• Purity: 98%
• Molecular weight: 261.09g/mol

Isophosphamide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 261.09

Ifosfamide

CAS: 3778-73-2

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₇H₁₅Cl₂N₂O₂P
• Color and Shape: Powder, White to almost white to light beige
• Molecular weight: 261.08

Ifosfamide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Color and Shape: Neat
• Molecular weight: 261.09

Ifosfamide - Bio-X ™

CAS: 3778-73-2

Ifosfamide is an alkylating agent and immunosuppressive drug used in chemotherapy for the treatment of …

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 261.09 g/mol

Ifosfamide

CAS: 3778-73-2

Alkylating agent; anti-cancer agent

• Formula: C₇H₁₅Cl₂N₂O₂P
• Purity: Min. 98 Area-%
• Color and Shape: White Off-White Powder
• Molecular weight: 261.09 g/mol

Ifosfamide

CAS: 3778-73-2

Applications A cytostatic agent, related structurally to cyclophosphamide. Not a dangerous good if item is …

• Formula: C₇H₁₅Cl₂N₂O₂P
• Color and Shape: Neat
• Molecular weight: 261.09

Ifosfamide

CAS: 3778-73-2

• Formula: C₇H₁₅Cl₂N₂O₂P
• Color and Shape: Neat
• Molecular weight: 261.09

3-(2-Chloroethyl)-2-[(2-chloroethyl)amino]perhydrochloroethyl)amino]perhydro-2H-1,3,2-oxazaphosphorineoxide

CAS: 3778-73-2

• Purity: 97%
• Molecular weight: 261.08