CAS 37926-75-3

(9xi,11beta,16beta)-9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid

Description:

The chemical substance known as (9xi,11beta,16beta)-9-fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid, with the CAS number 37926-75-3, is a synthetic steroid compound that exhibits anti-inflammatory and immunosuppressive properties. It belongs to the class of corticosteroids, which are characterized by their steroid structure and the presence of functional groups that contribute to their biological activity. This compound features a fluorine atom, hydroxyl groups, and a carboxylic acid moiety, which enhance its potency and efficacy in therapeutic applications. The presence of the 3-oxo group and the diene structure is significant for its interaction with biological receptors. Its specific stereochemistry, indicated by the nomenclature, plays a crucial role in determining its pharmacological effects. This compound is often studied for its potential use in treating various inflammatory conditions and may also be investigated for its effects on metabolic pathways. As with many steroid derivatives, its use must be carefully managed due to potential side effects and regulatory considerations.

Formula: C₂₁H₂₇FO₅

InChI: InChI=1/C21H27FO5/c1-11-8-15-14-5-4-12-9-13(23)6-7-18(12,2)20(14,22)16(24)10-19(15,3)21(11,27)17(25)26/h6-7,9,11,14-16,24,27H,4-5,8,10H2,1-3H3,(H,25,26)/t11-,14-,15-,16-,18-,19-,20?,21?/m0/s1

Betamethasone Impurity 3 (Betamethasone 17-Carboxylic Acid)

CAS: 37926-75-3

Formula: C₂₁H₂₇FO₅

Color and Shape: White To Off-White Solid

Molecular weight: 378.44

Ref: 4Z-B-065041

Betamethasone Acid

Controlled Product

CAS: 37926-75-3

Applications Betamethasone Acid is a derivative of Betamethasone (B327000), a gluccocorticoid used as an anti-inflammatory agent.
References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),

Formula: C₂₁H₂₇FO₅

Color and Shape: Neat

Molecular weight: 378.43

Ref: TR-B327125

Betamethasone acid

Controlled Product

CAS: 37926-75-3

Betamethasone acid is a corticosteroid that is used to treat inflammatory skin diseases such as psoriasis and eczema. It has been shown to be effective in treating various inflammatory diseases, such as asthma, arthritis, and Crohn's disease. Betamethasone acid inhibits the production of e3 ubiquitin ligase proteins which are involved in the degradation of proteins. This inhibition leads to an increase in protein synthesis and decreased inflammation. Betamethasone acid also blocks the activity of inflammatory cells by binding to specific receptors on their surfaces and prevents them from releasing inflammatory substances. Betamethasone acid is also used to treat skin conditions such as dermatitis and erythroderma, but it can cause side effects including hyperglycemia, increased appetite, weight gain, insomnia, depression, anxiety, or mood swings.

Formula: C₂₁H₂₇FO₅

Purity: Min. 95%

Molecular weight: 378.4 g/mol

Ref: 3D-MBA92675

Betamethasone Sodium Phosphate Impurity G

CAS: 37926-75-3

Formula: C₂₁H₂₇FO₅

Molecular weight: 378.44

Ref: ST-EA-CP-B92007