
CAS 381168-77-0
:Formula:C19H12F2N4
InChI:InChI=1S/C19H12F2N4/c20-15-6-5-13(11-16(15)21)23-19-14-3-1-2-4-17(14)24-18(25-19)12-7-9-22-10-8-12/h1-11H,(H,23,24,25)
InChI key:LBPYNNJXARHGAG-UHFFFAOYSA-N
SMILES:C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=NC=C3)NC4=CC(=C(C=C4)F)F
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ML367
CAS:ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.Formula:C19H12F2N4Purity:99.39%Color and Shape:SolidMolecular weight:334.3222ML367
CAS:ML367 is a reactive, cytotoxic molecule that is used in the treatment of cancer. It preferentially stabilizes damaged DNA molecules and prevents their repair. ML367 has also been shown to have damaging effects on cells, including carboxy-terminal deoxynucleotidyl transferase (CTD) activity, hydroxy group formation, and adenosine diphosphate ribose (ADP-ribose) hydrolysis. This chemical can be applied to cells in aqueous solution or as a solubilized form for the purpose of disrupting cellular adhesion and/or cell-cell interactions.Formula:C19H12F2N4Purity:Min. 95%Molecular weight:334.32 g/mol




