CAS 382-67-2

Desoximetasone

Description:

Desoximetasone is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties in dermatological applications. It is characterized by its ability to reduce inflammation, itching, and redness associated with various skin conditions, such as eczema and psoriasis. The compound exhibits a high potency relative to other topical corticosteroids, making it effective in treating moderate to severe skin disorders. Desoximetasone is typically formulated in topical preparations, including creams and ointments, allowing for localized treatment with minimal systemic absorption. Its mechanism of action involves the inhibition of inflammatory mediators and modulation of immune responses. The substance is generally well-tolerated, although potential side effects may include skin irritation, atrophy, or systemic effects with prolonged use. As with all corticosteroids, it is important to use desoximetasone under medical supervision to minimize risks and ensure appropriate therapeutic outcomes.

Formula: C₂₂H₂₉FO₄

InChI: InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1

InChI key: InChIKey=VWVSBHGCDBMOOT-IIEHVVJPSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@@H](C(CO)=O)[C@H](C)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• (11β,16α)-9-Fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• (8Xi,10Xi,13Xi,14Xi,16Alpha,17Xi)-9-Fluoro-11,21-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• 17-Deoxydexamethasone
• 17-Deoxymethansone
• 17-Deoxymethasone
• 17-Desoximethasone
• 9-Fluoro-11-beta,21-dihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-16α-methyl-Δ1-corticosterone
• 9-Fluoro-16α-methyl-Δ¹-corticosterone
• 9α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione
• A 41-304
• A 41304
• Brn 2228097
• Deoxymethasone
• Desossimetasone
• Desossimetasone [DCIT]
• Desoximetason
• Desoximetasona
• Desoximetasona [INN-Spanish]
• Desoximetasone [USAN:INN]
• Desoximetasonum
• Desoximetasonum [INN-Latin]
• Desoximethasone
• Desoxymetasone
• Desoxymethasone
• Esperson
• Flubason
• Hoe 304
• Ibaril
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11beta,16alpha)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,21-dihydroxy-16α-methyl-
• R 2113
• Stidex
• Stiedex
• Topicort
• Topicort LP
• Topicorte
• Topisolon

9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione

Controlled Product

CAS: 382-67-2

9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione is a potent antiandrogen that is used to treat alopecia areata and other skin disorders. 9-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione has been shown to have an inhibitory effect on the growth of skin tumors in mice. This drug also has a protective effect against chemical stability. It binds to fatty acids and epidermal growth factor (EGF), which may be related to its ability to regulate transcriptional processes and inflammatory skin diseases.

Formula: C₂₂H₂₉FO₄

Purity: Min. 95%

Molecular weight: 376.46 g/mol

Ref: 3D-FF21375