CAS 383-50-6

2-Fluoroethyl 4-methylbenzenesulfonate

Description:

2-Fluoroethyl 4-methylbenzenesulfonate, with the CAS number 383-50-6, is an organic compound characterized by its sulfonate ester functional group. It features a 4-methylbenzenesulfonate moiety, which contributes to its aromatic properties and potential reactivity. The presence of the fluoroethyl group enhances its electrophilic character, making it a useful intermediate in organic synthesis, particularly in the formation of carbon-fluorine bonds. This compound is typically a colorless to pale yellow liquid and is soluble in organic solvents. Its reactivity is influenced by the sulfonate group, which can facilitate nucleophilic substitution reactions. Additionally, the fluorine atom can impart unique properties such as increased lipophilicity and stability against hydrolysis. Due to these characteristics, 2-fluoroethyl 4-methylbenzenesulfonate is of interest in medicinal chemistry and materials science, where it may serve as a building block for more complex molecules. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₉H₁₁FO₃S

InChI: InChI=1/C9H11FO3S/c1-8-2-4-9(5-3-8)14(11,12)13-7-6-10/h2-5H,6-7H2,1H3

SMILES: Cc1ccc(cc1)S(=O)(=O)OCCF

Synonyms:

• Fluoroethyl 4-toluenesulfonate

2-Fluoroethyl 4-methylbenzenesulfonate

CAS: 383-50-6

2-Fluoroethyl 4-methylbenzenesulfonate

Formula: C₉H₁₁FO₃S

Purity: 97%

Molecular weight: 218.25

Ref: IN-DG75154

2-Fluoroethyl 4-methylbenzenesulfonate

CAS: 383-50-6

Formula: C₉H₁₁FO₃S

Purity: 98%

Color and Shape: Liquid

Molecular weight: 218.2452

Ref: IN-DA00BYE9

2-Fluoroethyl 4-methylbenzenesulfonate

CAS: 383-50-6

2-Fluoroethyl 4-methylbenzenesulfonate

Formula: C₉H₁₁FO₃S

Purity: 98%

Color and Shape: Liquid

Molecular weight: 218.24524

Ref: 54-PC902702

Fluoroethyl 4-toluenesulfonate

CAS: 383-50-6

Ref: 7W-GK7614

2-Fluoroethyl p-Toluenesulfonate

CAS: 383-50-6

Formula: C₉H₁₁FO₃S

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 218.24

Ref: 3B-F1056

2-Fluoroethyl tosylate

CAS: 383-50-6

2-Fluoroethyl tosylate is a potent antagonist of the benzodiazepine receptor that is used in vivo to measure the affinity and selectivity of ligands. The 2-fluoroethyl tosylate binds reversibly to the benzodiazepine receptor, so that it can be easily displaced by another ligand. This process can be quantified using positron emission tomography (PET) or optical imaging. 2-Fluoroethyl tosylate has also been used as a radiotracer for cardiac imaging and tumor xenografts. It is also used for studying glutamate receptors and uptake mechanisms in cells. The salt form of 2-fluoroethyl tosylate is sodium salts, which are water soluble and stable at high temperatures, making them useful for in vivo studies.

Formula: C₉H₁₁FO₃S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.25 g/mol

Ref: 3D-FF29461

2-Fluoroethyl 4-methylbenzenesulfonate

CAS: 383-50-6

Formula: C₉H₁₁FO₃S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 218.24

Ref: 10-F222288

2-Fluoroethyl Tosylate

Controlled Product

CAS: 383-50-6

Applications 2-Fluoroethyl Tosylate is an intermediate used in the preparation and pre-clinical evaluation of new class of high-affinity 18F-labeled PSMA ligands for detection of prostate cancer by positron emission tomography (PET) imaging.
References Kelly, J., et al.: Eur. J. Nucl. Med. Mol. Imaging, 44, 647 (2017)

Formula: C₉H₁₁FO₃S

Color and Shape: Neat

Molecular weight: 218.25

Ref: TR-F591735