CAS 385800-16-8

(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261)

Description:

(S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate, also known by its CAS number 385800-16-8, is a chemical compound characterized by its complex structure that includes a methylsulfonyl group and a naphthalene derivative. This compound typically exhibits properties associated with esters, such as being relatively non-volatile and having moderate solubility in organic solvents. The presence of the methylsulfonyl group may impart unique polar characteristics, potentially influencing its reactivity and interaction with biological systems. The naphthalene moiety contributes to its aromatic properties, which can affect its stability and potential applications in pharmaceuticals or organic synthesis. Additionally, the stereochemistry indicated by the (S) configuration suggests that it may exhibit specific biological activity or selectivity, making it of interest in medicinal chemistry. Overall, this compound's unique structural features suggest potential utility in various chemical and biological applications, although specific data on its reactivity and biological effects would require further investigation.

Formula: C₁₇H₂₀O₅S

Synonyms:

• MX 1094
• 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, 2-(methylsulfonyl)ethyl ester, (αS)-
• (S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate
• (S)-2-(methylsulfonyl)ethyl 2-(6-methoxynaphthalen-2-yl)propanoate(WXG02261)
• LT-NS 001
• Naproxen etemesil

Naproxen etemesil

CAS: 385800-16-8

Naproxen etemesil is a prodrug of naproxen. It is used to treat inflammation, pain, and fever. Naproxen etemesil has been shown to be effective in the treatment of inflammatory bowel disease (IBD) and ulcerative colitis (UC), but not Crohn's disease. Naproxen etemesil has been shown to be safe and tolerable at doses of 400 mg per day, but may lead to increased risk of cardiovascular events at higher doses. The drug also has a low body mass index (BMI) safety profile, which can make it an appropriate treatment for patients with a BMI below 30. Naproxen etemesil is the first prodrug of naproxen that can be given by continuous pump infusion, which may improve prognosis in patients with cancer or inflammatory diseases.

Formula: C₁₇H₂₀O₅S

Purity: Min. 95%

Molecular weight: 336.4 g/mol

Ref: 3D-KQA80016

Naproxen etemesil

CAS: 385800-16-8

Naproxen, a COX-1/2 inhibitor, has IC50s of 8.72/5.15 μM. Its prodrug, naproxen etemesil, is lipophilic and converts to active form upon absorption.

Formula: C₁₇H₂₀O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 336.4

Ref: TM-T16272