CAS 3863-11-4

3,4-Difluoroaniline

Description:

3,4-Difluoroaniline is an aromatic amine characterized by the presence of two fluorine atoms positioned at the 3 and 4 positions on the aniline ring. Its molecular formula is C6H5F2N, and it features a benzene ring with an amino group (-NH2) that contributes to its reactivity and solubility in polar solvents. This compound is typically a colorless to pale yellow liquid or solid, depending on temperature and purity. 3,4-Difluoroaniline is known for its applications in the synthesis of various pharmaceuticals, agrochemicals, and dyes, owing to its ability to undergo electrophilic substitution reactions. It is also of interest in materials science for its potential use in the development of fluorinated polymers. However, like many anilines, it may pose health risks, including toxicity and potential carcinogenicity, necessitating careful handling and appropriate safety measures during use. Its physical and chemical properties, such as boiling point, melting point, and solubility, can vary based on environmental conditions and specific formulations.

Formula: C₆H₅F₂N

InChI: InChI=1S/C6H5F2N/c7-5-2-1-4(9)3-6(5)8/h1-3H,9H2

InChI key: InChIKey=AXNUZKSSQHTNPZ-UHFFFAOYSA-N

SMILES: FC1=C(F)C=CC(N)=C1

Synonyms:

• 3,4-Difluoro Aniline
• 3,4-Difluorobenzenamine
• 3,4-Difluorophenylamine
• 4,5-Difluoroaniline
• Aniline, 3,4-difluoro-
• Benzenamine, 3,4-difluoro-
• N-methyl-N-(trifluoro-lambda~4~-sulfanyl)methanamine
• NSC 10296
• 3,4-Difluoroaniline

3,4-Difluoroaniline

CAS: 3863-11-4

Formula: C₆H₅F₂N

Purity: >98.0%(GC)(T)

Color and Shape: White or Colorless to Yellow powder to lump to clear liquid

Molecular weight: 129.11

Ref: 3B-D1809

3,4-Difluoroaniline

CAS: 3863-11-4

Formula: C₆H₅F₂N

Purity: 98%

Color and Shape: Liquid

Molecular weight: 129.1074

Ref: IN-DA0033II

3,4-Difluoroaniline

CAS: 3863-11-4

3,4-Difluoroaniline

Formula: C₆H₅F₂N

Purity: 97%

Color and Shape: clear. dark brown liquid

Molecular weight: 129.11g/mol

Ref: 54-PC2612

3,4-Difluoroaniline

CAS: 3863-11-4

Formula: C₆H₅F₂N

Molecular weight: 129.11

Ref: 7W-GK8386

3,4-Difluoroaniline-2,6-d2

CAS: 1061566-62-8, 3863-11-4

Purity: 99 atom % D

Molecular weight: 131.11

Ref: 3U-D7984

Gefitinib Impurity 35 (3,4-Difluoroaniline)

CAS: 3863-11-4

Formula: C₆H₅F₂N

Molecular weight: 129.11

Ref: 4Z-G-2355

3,4-Difluoroaniline

CAS: 3863-11-4

Formula: C₆H₅F₂N

Purity: 98%

Color and Shape: Liquid, Low Melting Solid

Molecular weight: 129.11

Ref: 10-F001459

3,4-Difluoroaniline

Controlled Product

CAS: 3863-11-4

Applications 3,4-Difluoroaniline was used to prepare thiourea-containing sorafenib analogs or fluorinated 2-(4-aminophenyl)benzothiazoles as potential antitumor agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yao, J., et al.: Bioorg. Med. Chem., 20, 2923 (2012); Hutchinson, I., et al.: J. Med. Chem., 44, 1446 (2001)

Formula: C₆H₅F₂N

Color and Shape: Neat

Molecular weight: 129.11

Ref: TR-D445340