CAS 387-79-1

17-Hydroxypregnenolone

Description:

17-Hydroxypregnenolone is a steroid hormone that serves as a precursor in the biosynthesis of other steroid hormones, including progesterone and cortisol. It is derived from pregnenolone through the action of the enzyme 17α-hydroxylase. This compound is characterized by its steroid structure, which includes a four-ring carbon framework typical of steroids, with a hydroxyl group (-OH) at the 17th carbon position. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents but has limited solubility in water. 17-Hydroxypregnenolone plays a significant role in the adrenal cortex and is involved in the regulation of various physiological processes, including stress response and metabolism. Its levels can be influenced by factors such as age, sex, and health status. In clinical settings, it may be measured to assess adrenal function or diagnose certain disorders related to steroidogenesis. As with many steroid hormones, it is important to handle 17-hydroxypregnenolone with care due to its biological activity and potential effects on hormonal balance.

Formula: C₂₁H₃₂O₃

InChI: InChI=1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3/t15-,16+,17-,18-,19-,20-,21-/m0/s1

InChI key: InChIKey=JERGUCIJOXJXHF-TVWVXWENSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Synonyms:

• (3Beta,14Xi)-3,17-Dihydroxypregn-5-En-20-One
• (3beta)-3,17-Dihydroxypregn-5-en-20-one
• (3β)-3,17-Dihydroxypregn-5-en-20-one
• 17-Hydroxy-Δ5-pregnenolone
• 17-Hydroxy-Δ⁵-pregnenolone
• 17-Hydroxypregnenolone
• 17alpha-Hydroxypregnenolone
• 3,17-Dihydroxypregn-5-En-20-One
• 3-Beta,17-Alpha-Dihydroxypregn-5-En-20-One
• 3-Β,17-Α-Dihidroxipregn-5-En-20-Ona
• 3-Β,17-Α-Dihydroxypregn-5-En-20-One
• 3-Β,17-Α-Dihydroxypregn-5-Ene-20-One
• 3-β,17-α-Dihydroxypregn-5-en-20-on
• 3b,17-Dihydroxy-5-pregnen-20-one
• 3b,17-dihydroxy-Pregn-5-en-20-one
• 3b,17a-Dihydroxypregn-5-en-20-one
• 3beta,17alpha-Dihydroxy-5-pregnen-20-one
• 5-Pregnen-3β,17α-diol-20-one
• Hydroxypregnenolone
• Nsc 63853
• Pregn-5-En-20-One, 3,17-Dihydroxy-, (3Beta)-
• Pregn-5-en-20-one, 3,17-dihydroxy-, (3.beta.)-
• Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)-
• Pregn-5-en-20-one, 3.beta.,17-dihydroxy-
• Pregn-5-en-20-one, 3β,17-dihydroxy-
• 17α-Hydroxypregnenolone

Pregn-5-en-20-one, 3,17-dihydroxy-, (3b)-

CAS: 387-79-1

Formula: C₂₁H₃₂O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 332.4770

Ref: IN-DA00I7OD

17a-Hydroxypregnenolone

CAS: 387-79-1

17a-Hydroxypregnenolone

Purity: ≥98%

Molecular weight: 332.48g/mol

Ref: 54-BUP11678

17-Hydroxy Pregnenolone

CAS: 387-79-1

Formula: C₂₁H₃₂O₃

Molecular weight: 332.48

Ref: 4Z-P-245001

17a-Hydroxypregnenolone

CAS: 387-79-1

17a-Hydroxypregnenolone is a pregnane steroid. It is a prohormone in the formation of dehydroepiandrosterone (DHEA).

Formula: C₂₁H₃₂O₃

Purity: 99.38% - 99.76%

Color and Shape: Solid

Molecular weight: 332.48

Ref: TM-T10048

17-Hydroxy Pregnenolone

Controlled Product

CAS: 387-79-1

Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).
References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),

Formula: C₂₁H₃₂O₃

Color and Shape: White To Off-White

Molecular weight: 332.48

Ref: TR-H952320

17alpha-Hydroxypregnenolone

Controlled Product

CAS: 387-79-1

17alpha-Hydroxypregnenolone is a steroid hormone that has been shown to have effects on the metabolism of lipids, glucose and protein. This compound is synthesized from progesterone by the enzyme 17alpha-hydroxylase and is converted to 17beta-hydroxyprogesterone by the enzyme 17,20 lyase. It has been shown to have an effect on body mass index in humans and model organisms such as mice. The tissue culture studies showed that 17alpha-Hydroxypregnenolone led to an increase in serum bile acids. In adrenocortical carcinoma cell lines, this compound was found to inhibit the growth of cancer cells through inhibition of DNA synthesis and protein synthesis through inhibition of RNA polymerase II activity. It also inhibits infectious diseases by decreasing virus production and increasing the production of interferon alpha. When synthesized for use in experimental models, this compound can be used as a marker for metabolic disorders or cation

Formula: C₂₁H₃₂O₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 332.48 g/mol

Ref: 3D-FH40258

17-Hydroxy Pregnenolone

CAS: 387-79-1

Formula: C₂₁H₃₂O₃

Molecular weight: 332.48

Ref: ST-EA-CP-P135004