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CAS 387-79-1

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17-Hydroxypregnenolone

Description:
17-Hydroxypregnenolone is a steroid hormone that serves as a precursor in the biosynthesis of other steroid hormones, including progesterone and cortisol. It is derived from pregnenolone through the action of the enzyme 17α-hydroxylase. This compound is characterized by its steroid structure, which includes a four-ring carbon framework typical of steroids, with a hydroxyl group (-OH) at the 17th carbon position. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents but has limited solubility in water. 17-Hydroxypregnenolone plays a significant role in the adrenal cortex and is involved in the regulation of various physiological processes, including stress response and metabolism. Its levels can be influenced by factors such as age, sex, and health status. In clinical settings, it may be measured to assess adrenal function or diagnose certain disorders related to steroidogenesis. As with many steroid hormones, it is important to handle 17-hydroxypregnenolone with care due to its biological activity and potential effects on hormonal balance.
Formula:C21H32O3
InChI:InChI=1S/C21H32O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4,15-18,23-24H,5-12H2,1-3H3/t15-,16+,17-,18-,19-,20-,21-/m0/s1
InChI key:InChIKey=JERGUCIJOXJXHF-TVWVXWENSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]
Synonyms:
  • (3Beta,14Xi)-3,17-Dihydroxypregn-5-En-20-One
  • (3beta)-3,17-Dihydroxypregn-5-en-20-one
  • (3β)-3,17-Dihydroxypregn-5-en-20-one
  • 17-Hydroxy-Δ5-pregnenolone
  • 17-Hydroxy-Δ<sup>5</sup>-pregnenolone
  • 17-Hydroxypregnenolone
  • 17alpha-Hydroxypregnenolone
  • 3,17-Dihydroxypregn-5-En-20-One
  • 3-Beta,17-Alpha-Dihydroxypregn-5-En-20-One
  • 3-Β,17-Α-Dihidroxipregn-5-En-20-Ona
  • See more synonyms
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