CAS 389574-19-0
:Prasugrel hydrochloride
Description:
Prasugrel hydrochloride is an antiplatelet medication primarily used to reduce the risk of cardiovascular events in patients with acute coronary syndrome undergoing percutaneous coronary intervention. It is a thienopyridine derivative that acts as a prodrug, requiring metabolic activation to exert its pharmacological effects. The active metabolite irreversibly binds to the P2Y12 receptor on platelets, inhibiting ADP-mediated platelet activation and aggregation. This characteristic makes prasugrel more potent and faster-acting compared to some other antiplatelet agents. The hydrochloride salt form enhances its solubility and stability. Prasugrel is typically administered orally and is known for its favorable pharmacokinetic profile, including a rapid onset of action and a relatively short half-life. Common side effects may include bleeding complications, which necessitate careful patient selection and monitoring. Due to its mechanism of action, prasugrel is contraindicated in patients with a history of transient ischemic attacks or strokes. Overall, prasugrel hydrochloride is a critical therapeutic option in the management of acute coronary syndromes.
Formula:C20H20FNO3S·ClH
InChI:InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H
InChI key:InChIKey=JALHGCPDPSNJNY-UHFFFAOYSA-N
SMILES:C(C(=O)C1CC1)(N2CC3=C(CC2)SC(OC(C)=O)=C3)C4=C(F)C=CC=C4.Cl
Synonyms:- 2-Acetoxy-5-(α-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride
- 2-[2-(Acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)ethanone hydrochloride
- 5-[2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl]-4,5,6,7-Tetrahydrothieno[3,2-C]Pyridin-2-Yl Acetate Hydrochloride (1:1)
- Effient
- Efient
- Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-, hydrochloride
- Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-, hydrochloride (1:1)
- Prasu Doc
- Prasugrel hydrochloride
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Prasugrel Hydrochloride
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C20H20FNO3S·HClColor and Shape:White Off-White PowderMolecular weight:409.09147Prasugrel Hydrochloride
CAS:Prasugrel HydrochlorideFormula:C20H20FNO3S·HClPurity:≥98%Molecular weight:409.9Prasugrel Hydrochloride
CAS:Prasugrel HydrochlorideFormula:C20H21ClFNO3SPurity:99%Molecular weight:409.9Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-, hydrochloride (1:1)
CAS:Formula:C20H21ClFNO3SPurity:99%Color and Shape:SolidMolecular weight:409.9020Prasugrel Hydrochloride
CAS:Controlled ProductFormula:C20H20FNO3S·ClHColor and Shape:NeatMolecular weight:409.9Prasugrel Hydrochloride
CAS:Controlled ProductApplications A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome
References Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),Formula:C20H20FNO3S·ClHColor and Shape:NeatMolecular weight:409.9Prasugrel Hydrochloride
CAS:Prasugrel Hydrochloride (LY 640315 Hydrochloride) is pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.Formula:C20H21ClFNO3SPurity:99.79% - 99.80%Color and Shape:SolidMolecular weight:409.902Prasugrel hydrochloride
CAS:Formula:C20H20FNO3S·HClPurity:98.0 - 102.0 % (dried basis)Color and Shape:White to off-white powderMolecular weight:409.90Prasugrel HCl
CAS:5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate hydrochlorideFormula:C20H21ClFNO3SPurity:99%Molecular weight:409.9Ethanone, 2-[2-(acetyloxy)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl]-1-cyclopropyl-2-(2-fluorophenyl)-, hydrochloride (1:1)
CAS:Purity:99%Molecular weight:409.8999939
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