CAS 395-35-7

4-(Trifluoromethyl)mandelic acid

Description:

4-(Trifluoromethyl)mandelic acid, with the CAS number 395-35-7, is an aromatic compound characterized by the presence of a trifluoromethyl group (-CF3) attached to the aromatic ring of mandelic acid. This compound typically appears as a white crystalline solid and is known for its unique chemical properties, which are influenced by the electronegative trifluoromethyl group. The presence of this group enhances the compound's lipophilicity and can affect its reactivity and interaction with biological systems. 4-(Trifluoromethyl)mandelic acid is often utilized in organic synthesis and medicinal chemistry, where it may serve as an intermediate in the production of pharmaceuticals or agrochemicals. Its solubility in organic solvents and limited solubility in water are notable characteristics, which can impact its application in various chemical processes. Additionally, the compound's stability under standard conditions makes it a valuable building block in synthetic organic chemistry. Safety precautions should be observed when handling this compound, as with many fluorinated organic substances, due to potential toxicity and environmental concerns.

Formula: C₉H₇F₃O₃

InChI: InChI=1S/C9H7F3O3/c10-9(11,12)6-3-1-5(2-4-6)7(13)8(14)15/h1-4,7,13H,(H,14,15)

InChI key: InChIKey=SDGXYUQKJPFLDG-UHFFFAOYSA-N

SMILES: C(C(O)=O)(O)C1=CC=C(C(F)(F)F)C=C1

Synonyms:

• (2R)-hydroxy[4-(trifluoromethyl)phenyl]ethanoate
• (2S)-hydroxy[4-(trifluoromethyl)phenyl]ethanoate
• 2-(4-(Trifluoromethyl)phenyl)-2-hydroxyacetic acid
• 2-Hydroxy-2-(4-trifluoromethylphenyl)acetic acid
• 2-Hydroxy-2-[4-(trifluoromethyl)phenyl]acetic acid
• 4-(Trifluoromethyl)mandelic acid
• 4-(Trifluoromethyl)mandelicacid
• 4-Trifluoromethylmandelic acid
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-4-(Trifluoromethyl)mandelic acid
• Benzeneacetic acid, α-hydroxy-4-(trifluoromethyl)-
• Hydroxy[4-(Trifluoromethyl)Phenyl]Acetic Acid
• Mandelic acid, 4-(trifluoromethyl)-
• p-(Trifluoromethyl)mandelic acid

4-(Trifluoromethyl)mandelic acid, 98%

CAS: 395-35-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₇F₃O₃

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 220.15

Ref: 02-B22264

4-(Trifluoromethyl)mandelic acid

CAS: 395-35-7

4-(Trifluoromethyl)mandelic acid

Formula: C₉H₇F₃O₃

Purity: 98%

Color and Shape: White Solid-Powder

Molecular weight: 220.14528

Ref: 54-PC7687

4-(Trifluoromethyl)mandelic acid

CAS: 395-35-7

Formula: C₉H₇F₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 220.1453

Ref: IN-DA00BZBN

4-(Trifluoromethyl)mandelic acid

CAS: 395-35-7

Formula: C₉H₇F₃O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 220.147

Ref: 10-F007628

2-Hydroxy-2-(4-(trifluoromethyl)phenyl)acetic acid

CAS: 395-35-7

2-Hydroxy-2-(4-(trifluoromethyl)phenyl)acetic acid

Formula: C₉H₇F₃O₃

Purity: 98%

Molecular weight: 220.15

Ref: IN-DG7417

4-(Trifluoromethyl)mandelic acid

CAS: 395-35-7

4-(Trifluoromethyl)mandelic acid (4-TFA) is a metabolite of the drug mandelic acid. It is a thermodynamically stable, stereospecific, and highly polar compound that can be easily purified by column chromatography. 4-TFA has been shown to have analytical methods in common with mandelic acid, including fluorine analysis and regression. The chemical properties of 4-TFA are similar to those of other aldehydes. It also has enantiomeric purity and can be analysed using gas chromatography-mass spectrometry in urine samples.

Formula: C₉H₇F₃O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 220.15 g/mol

Ref: 3D-FT63987