CAS 396-01-0

Triamterene

Description:

Triamterene is a potassium-sparing diuretic primarily used in the treatment of hypertension and edema. It is classified as a non-thiazide diuretic and works by inhibiting sodium reabsorption in the distal convoluted tubule and collecting ducts of the nephron, leading to increased excretion of sodium and water while conserving potassium. Triamterene is typically administered orally and is often combined with other diuretics to enhance its efficacy and mitigate potassium loss. The substance is characterized by its relatively low solubility in water, which can affect its absorption and bioavailability. Chemically, it has a molecular formula that includes carbon, hydrogen, nitrogen, and sulfur, contributing to its unique properties. Side effects may include hyperkalemia, gastrointestinal disturbances, and dizziness. Due to its mechanism of action, triamterene is particularly useful in patients at risk of hypokalemia from other diuretics. As with any medication, it is essential to monitor renal function and electrolyte levels during treatment.

Formula: C₁₂H₁₁N₇

InChI: InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)

InChI key: InChIKey=FNYLWPVRPXGIIP-UHFFFAOYSA-N

SMILES: NC=1C2=C(N=C(N)C(=N2)C3=CC=CC=C3)N=C(N)N1

Synonyms:

• 2,4,7-Pteridinetriamine, 6-phenyl-
• 2,4,7-Triamino-6-phenylpteridine
• 6-Phenyl-2,4,7-pteridinetriamine
• 6-Phenyl-2,4,7-triaminopteridine
• Ademin
• Ademine
• Diren
• Ditak
• Diurene
• Dyren
• Dyrenium
• Dytac
• Jatropur
• Noridil
• Nsc 77625
• Pteridine, 2,4,7-triamino-6-phenyl-
• Pterofen
• Pterophene
• Skf 8542
• Taturil
• Teriam
• Teridin
• Tri-Span
• Triampur
• Triamteren
• Triamterena
• Triamterenum
• Triamteril
• Triamteril complex
• Triteren

2,4,7-Triamino-6-phenylpteridine, 98%

CAS: 396-01-0

Weak diuretic with potassium sparing properties that blocks sodium reuptake in the kidneys This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product /

Formula: C₁₂H₁₁N₇

Purity: 98%

Color and Shape: Powder, Yellow

Molecular weight: 253.27

Ref: 02-B20044

Triamterene

CAS: 396-01-0

Color and Shape: Neat

Ref: 61-FOR0269.00

Triamterene 1.0 mg/ml in Dimethyl Sulfoxide

CAS: 396-01-0

Color and Shape: Single Solution

Ref: 61-AMP0269.00-29

TRIAMTERENE CRS

CAS: 396-01-0

TRIAMTERENE CRS

Formula: C₁₂H₁₁N₇

Color and Shape: Crystalline Powder. Yellow. Powder.

Molecular weight: 253.2626

Ref: 41-Y0000837

Triamterene

CAS: 396-01-0

Triamterene

Formula: C₁₂H₁₁N₇

Purity: 99.2%

Color and Shape: Yellow Solid

Molecular weight: 253.10759

Ref: 47-340

Triamterene

CAS: 396-01-0

Aromatic or modified aromatic drugs with nitrogen hetero-atom(s) only, not elsewhere specified or included

Formula: C₁₂H₁₁N₇

Color and Shape: Yellow Crystalline Powder

Molecular weight: 253.26

Ref: 45-1680007

Triamterene

CAS: 396-01-0

Formula: C₁₂H₁₁N₇

Molecular weight: 253.27

Ref: 7W-GL2461

Triamterene

CAS: 396-01-0

Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner.

Formula: C₁₂H₁₁N₇

Purity: 99.77%

Color and Shape: Yellow Yellow Solid

Molecular weight: 253.26

Ref: TM-T0843

Triamterene

CAS: 396-01-0

Formula: C₁₂H₁₁N₇

Color and Shape: Yellow Solid

Molecular weight: 253.27

Ref: 4Z-T-631

Triamterene

CAS: 396-01-0

Formula: C₁₂H₁₁N₇

Color and Shape: Neat

Molecular weight: 253.26

Ref: 04-C17641000

Triamterene

Controlled Product

CAS: 396-01-0

Formula: C₁₂H₁₁N₇

Color and Shape: Neat

Molecular weight: 253.26

Ref: 86-MM0269.00

6-Phenylpteridine-2,4,7-triamine

CAS: 396-01-0

6-Phenylpteridine-2,4,7-triamine

Purity: ≥95%

Color and Shape: Yellow Powder

Molecular weight: 253.26g/mol

Ref: 54-OR18575

Triamterene

CAS: 396-01-0

Formula: C₁₂H₁₁N₇

Color and Shape: Neat

Molecular weight: 253.26

Ref: TR-T767325

Triamterene

Controlled Product

CAS: 396-01-0

Epithelial sodium channel blocker; diuretic

Formula: C₁₂H₁₁N₇

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 253.26 g/mol

Ref: 3D-FT28388

2,4,7-Triamino-6-Phenylpteridine

CAS: 396-01-0

Formula: C₁₂H₁₁N₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 253.2626

Ref: IN-DA003FOL