CAS 396-01-0: Triamterene
Description:Triamterene is a potassium-sparing diuretic primarily used in the treatment of hypertension and edema. It is classified as a non-thiazide diuretic and works by inhibiting sodium reabsorption in the distal convoluted tubule and collecting ducts of the nephron, leading to increased excretion of sodium and water while conserving potassium. Triamterene is typically administered orally and is often combined with other diuretics to enhance its efficacy and mitigate potassium loss. The substance is characterized by its relatively low solubility in water, which can affect its absorption and bioavailability. Chemically, it has a molecular formula that includes carbon, hydrogen, nitrogen, and sulfur, contributing to its unique properties. Side effects may include hyperkalemia, gastrointestinal disturbances, and dizziness. Due to its mechanism of action, triamterene is particularly useful in patients at risk of hypokalemia from other diuretics. As with any medication, it is essential to monitor renal function and electrolyte levels during treatment.
Formula:C12H11N7
InChI:InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)
InChI key:InChIKey=FNYLWPVRPXGIIP-UHFFFAOYSA-N
SMILES:N1=C(N=C(N)C2=NC(=C(N=C12)N)C3=CC=CC=C3)N
- Synonyms:
- 2,4,7-Pteridinetriamine, 6-phenyl-
- 2,4,7-Triamino-6-phenylpteridine
- 6-Phenyl-2,4,7-pteridinetriamine
- 6-Phenyl-2,4,7-triaminopteridine
- Ademin
- Ademine
- Diren
- Ditak
- Diurene
- Dyren
- See more synonyms
- Dyrenium
- Dytac
- Jatropur
- Noridil
- Nsc 77625
- Pteridine, 2,4,7-triamino-6-phenyl-
- Pterofen
- Pterophene
- Skf 8542
- Taturil
- Teriam
- Teridin
- Tri-Span
- Triampur
- Triamteren
- Triamterena
- Triamterenum
- Triamteril
- Triamteril complex
- Triteren
- Urocaudal
