CAS 3978-80-1

BOC-L-tyrosine

Description:

BOC-L-tyrosine, with the CAS number 3978-80-1, is a derivative of the amino acid tyrosine, characterized by the presence of a tert-butyloxycarbonyl (BOC) protecting group on the amino group. This modification enhances its stability and solubility, making it useful in peptide synthesis and other biochemical applications. BOC-L-tyrosine is typically a white to off-white crystalline powder, and it is soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO), but less soluble in water. The BOC group can be easily removed under acidic conditions, allowing for the regeneration of the free amino group for further reactions. This compound is often utilized in the synthesis of peptides and proteins, as it allows for the selective protection of functional groups during chemical reactions. Additionally, BOC-L-tyrosine can serve as a building block in the development of pharmaceuticals and biochemicals, contributing to research in medicinal chemistry and drug design.

Formula: C₁₄H₁₉NO₅

InChI: InChI=1S/C14H19NO5/c1-14(2,3)20-13(19)15-11(12(17)18)8-9-4-6-10(16)7-5-9/h4-7,11,16H,8H2,1-3H3,(H,15,19)(H,17,18)/t11-/m0/s1

InChI key: InChIKey=CNBUSIJNWNXLQQ-NSHDSACASA-N

SMILES: C([C@H](NC(OC(C)(C)C)=O)C(O)=O)C1=CC=C(O)C=C1

Synonyms:

• (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoic acid
• (2S)-2-[(tert-butoxycarbonyl)amino]-3-(4-hydroxyphenyl)propanoate
• (2S)-3-(4-Hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
• <span class="text-smallcaps">L</span>-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-
• BOC-<span class="text-smallcaps">L</span>-tyrosine
• Boc-Tyr-OH
• N-(tert-Butyloxycarbonyl)-<span class="text-smallcaps">L</span>-tyrosine
• N-(tert-butoxycarbonyl)-D-tyrosine
• N-(tert-butoxycarbonyl)-L-tyrosine
• N-(tert-butoxycarbonyl)tyrosine
• N-Boc-<span class="text-smallcaps">L</span>-tyrosine
• N-[(1,1-Dimethylethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• NSC 334307
• Tert-Butoxycarbonyl-Tyrosine
• Tyrosine, N-carboxy-, N-tert-butyl ester
• Tyrosine, N-carboxy-, N-tert-butyl ester, <span class="text-smallcaps">L</span>-
• tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-tyrosine
• L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-
• Tyrosine, N-carboxy-, N-tert-butyl ester, L-

N-(tert-Butoxycarbonyl)-L-tyrosine

CAS: 3978-80-1

Formula: C₁₄H₁₉NO₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 281.31

Ref: 3B-B1640

N-Boc-L-tyrosine, 98+%

CAS: 3978-80-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₄H₁₉NO₅

Purity: 98+%

Color and Shape: White to pale cream, Powder

Molecular weight: 281.31

Ref: 02-A10810

Boc-Tyr-OH

CAS: 3978-80-1

M03338 - Boc-Tyr-OH

Formula: C₁₄H₁₉NO₅

Purity: 97%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 281.308

Ref: 10-M03338

Boc-Tyr-OH

CAS: 3978-80-1

Bachem ID: 4000198.

Formula: C₁₄H₁₉NO₅

Purity: > 99%

Color and Shape: White

Molecular weight: 281.31

Ref: 01-4000198

N-(tert-Butyloxycarbonyl)-L-tyrosin

CAS: 3978-80-1

Formula: C₁₄H₁₉NO₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 281.3044

Ref: IN-DA003A7C

Boc-Tyr-OH

CAS: 3978-80-1

Formula: C₁₄H₁₉NO₅

Molecular weight: 281.31

Ref: 7W-GM1531

Boc-L-tyrosine

CAS: 3978-80-1

Boc-L-tyrosine

Formula: C₁₄H₁₉NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 281.30435

Ref: 54-BIT0718

BOC-L-Tyrosine extrapure, 99%

CAS: 3978-80-1

Formula: C₁₄H₁₉NO₅

Purity: min. 99%

Color and Shape: White to off white, Crystalline powder

Molecular weight: 281.30

Ref: SR-61475

N-Boc-L-tyrosine

Controlled Product

CAS: 3978-80-1

Applications N-Boc-L-tyrosine is an N-Boc-protected form of L-Tyrosine (T899975). L-Tyrosine is an essential amino acid that exhibits in vitro antioxidant and antiradical activities. L-Tyrosine is used as a precursor to synthesize catecholamines (e.g. Norepinephrine HCl [N674500]) in human keratinocytes, and also for the synthesis of proteins and thyroid hormones.
References Gülçin, ?.: Amino Acids, 32, 431 (2007); Langen, K., et al.: Nuc. Med. Biol., 29, 625 (2002); Schallreuter, K., et al.: J. Invest. Derm., 104, 953 (1995); Zhang, W., et al.: Neuropharmacology, 47, 438 (2004)

Formula: C₁₄H₁₉NO₅

Color and Shape: Neat

Molecular weight: 281.3

Ref: TR-B667825

Boc-Tyr-OH

CAS: 3978-80-1

Boc-Tyr-OH is a tyrosinase inhibitor that binds to the active site of the enzyme and prevents the oxidation of tyrosinase into dopa. It is an enantiopure, cyclic peptide with a chemical stability suitable for use in biological assays. Boc-Tyr-OH has been shown to inhibit the synthesis of melanin by binding to the active site of tyrosinase, which is found in skin cells called melanocytes. The amino function of this compound allows it to be synthesized from amines and hydroxyl group, which can be obtained from trifluoroacetic acid or chromatographic techniques.

Formula: C₁₄H₁₉NO₅

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 281.3 g/mol

Ref: 3D-FB29907