CAS 39824-26-5

6-Chloropurine-9-(2,3-isopropylidene)-b-d-ribfuraniside

Description:

6-Chloropurine-9-(2,3-isopropylidene)-β-D-ribofuranoside, with the CAS number 39824-26-5, is a nucleoside analog characterized by its purine base structure and a ribofuranoside sugar moiety. This compound features a chlorine atom at the 6-position of the purine ring, which can influence its biological activity and interaction with nucleic acid synthesis pathways. The isopropylidene group at the 9-position of the ribofuranoside enhances the stability of the molecule, making it less susceptible to hydrolysis. This structural modification can also affect its solubility and permeability, which are critical for its potential therapeutic applications. The compound may exhibit antiviral or anticancer properties, as many nucleoside analogs do, by interfering with nucleic acid metabolism in target cells. Its synthesis and characterization typically involve standard organic chemistry techniques, including protection and deprotection strategies for the sugar moiety. Overall, this compound represents a significant interest in medicinal chemistry for its potential roles in drug development.

Formula: C₁₃H₁₅ClN₄O₄

InChI: InChI=1/C13H15ClN4O4/c1-13(2)21-8-6(3-19)20-12(9(8)22-13)18-5-17-7-10(14)15-4-16-11(7)18/h4-6,8-9,12,19H,3H2,1-2H3

SMILES: CC1(C)OC2C(CO)OC(C2O1)n1cnc2c(Cl)ncnc12

Synonyms:

• 6-chloro-9-[2,3-O-(1-methylethylidene)pentofuranosyl]-9H-purine
• 6-Chloro-9-Beta-D-(2,3-Isopropylidene)Ribofuranosylpurine
• 6-chloro-9-[2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-9H-purine

9H-Purine, 6-chloro-9-[2,3-O-(1-methylethylidene)-b-D-ribofuranosyl]-

CAS: 39824-26-5

Formula: C₁₃H₁₅ClN₄O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 326.7356

Ref: IN-DA00I7TE

6-Chloro-9-(2'',3''-O-isopropylidene-b-D-ribofuranosyl)purine

CAS: 39824-26-5

Ref: 7W-GN1821

6-Chloro-9-[2,3-O-(1-Methylethylidene)-β-D-Ribofuranosyl]-9H-Purine

CAS: 39824-26-5

6-Chloro-9-[2,3-O-(1-Methylethylidene)-β-D-Ribofuranosyl]-9H-Purine

Purity: 97%

Molecular weight: 326.74g/mol

Ref: 54-OR1012010

6-Chloro-9-(2',3'-O-isopropylidene-β-D-ribofuranosyl)purine

CAS: 39824-26-5

Halo-nucleoside; intermediate - electrophile

Formula: C₁₃H₁₅ClN₄O₄

Color and Shape: Solid

Molecular weight: 326.74

Ref: TM-TNU0747

6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside)

Controlled Product

CAS: 39824-26-5

Applications 6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside) (cas# 39824-26-5) is a compound useful in organic synthesis.

Formula: C₁₃H₁₅ClN₄O₄

Color and Shape: Neat

Molecular weight: 326.74

Ref: TR-C379885

6-Chloro-9-[2,3-O-(1-methylethylidene)-β-D-ribofuranosyl]-9H-Purine

CAS: 39824-26-5

Formula: C₁₃H₁₅ClN₄O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 326.74

Ref: 10-F092383

6-Chloro-9-(2',3'-O-isopropylidene-b-D-ribofuranosyl)purine

CAS: 39824-26-5

6-Chloro-9-(2',3'-O-isopropylidene-b-D-ribofuranosyl)purine is a nucleoside that is modified by adding an isopropylidene group (i.e., a C=C bond). It is used in the synthesis of oligonucleotides and phosphoramidites. 6-Chloro-9-(2',3'-O-isopropylidene-b-D-ribofuranosyl)purine has been shown to be an activator of the DNA polymerase, which increases its rate of incorporation of deoxyribonucleotide triphosphates into DNA chains. This nucleoside also has antiviral properties and can be used as an anticancer drug, specifically for hematological malignancies such as leukemia. 6-Chloro-9-(2',3'-O-isopropylidene

Formula: C₁₃H₁₅ClN₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 326.74 g/mol

Ref: 3D-NC04682