CAS 398493-79-3

PHA-680632

CAS: 398493-79-3

Formula: C₂₈H₃₅N₇O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 501.6232

Ref: IN-DA00C6H7

N-(2,6-Diethylphenyl)-3-(4-(4-Methylpiperazin-1-Yl)Benzamido)-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxamide

CAS: 398493-79-3

N-(2,6-Diethylphenyl)-3-(4-(4-Methylpiperazin-1-Yl)Benzamido)-4,6-Dihydropyrrolo[3,4-C]Pyrazole-5(1H)-Carboxamide

Purity: 99%+

Molecular weight: 501.62g/mol

Ref: 54-OR1023181

PHA-680632

CAS: 398493-79-3

PHA-680632

Purity: ≥98%

Molecular weight: 501.62g/mol

Ref: 54-BUP06086

PHA-680632

CAS: 398493-79-3

PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.

Formula: C₂₈H₃₅N₇O₂

Purity: 98.2%

Color and Shape: Solid

Molecular weight: 501.62

Ref: TM-T6338

PHA-680632

CAS: 398493-79-3

PHA-680632 is a potent and selective small-molecule inhibitor of Aurora kinases, which are serine/threonine kinases involved in crucial processes during mitosis. Sourced from synthesized chemical compounds, this inhibitor specifically targets Aurora kinases A, B, and C, disrupting their role in cell cycle regulation. The mode of action involves binding to the ATP-binding site of these kinases, leading to the inhibition of their activity and subsequently arresting cell cycle progression at the mitotic phase.

Formula: C₂₈H₃₅N₇O₂

Purity: Min. 95%

Molecular weight: 501.62 g/mol

Ref: 3D-YQA49379