CAS 399-52-0
:5-Fluoroindole
Description:
5-Fluoroindole is a heterocyclic organic compound characterized by the presence of a fluorine atom at the 5-position of the indole ring system. Its molecular formula is C8H6FN, and it features a bicyclic structure composed of a benzene ring fused to a pyrrole ring. This compound is typically a white to light yellow solid and is known for its aromatic properties, which contribute to its stability and reactivity. 5-Fluoroindole is of interest in medicinal chemistry and material science due to its potential applications in drug development and as a building block for synthesizing more complex molecules. The presence of the fluorine atom can enhance the lipophilicity and metabolic stability of derivatives, making them more effective in biological systems. Additionally, 5-fluoroindole can participate in various chemical reactions, including electrophilic substitutions and coupling reactions, which are valuable in synthetic organic chemistry. Safety data indicates that, like many fluorinated compounds, it should be handled with care due to potential toxicity and environmental concerns.
Formula:C8H6FN
InChI:InChI=1S/C8H6FN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
InChI key:InChIKey=ODFFPRGJZRXNHZ-UHFFFAOYSA-N
SMILES:c1cc2c(cc[nH]2)cc1F
Synonyms:- 1H-Indole, 5-fluoro-
- 5-Fluoro Indole
- 5-Fluoro-1H-indole
- Indole, 5-fluoro-
- NSC 88613
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5-Fluoroindole
CAS:Formula:C8H6FNPurity:>98.0%(GC)Color and Shape:White to Gray to Brown powder to crystalMolecular weight:135.145-Fluoroindole, 99%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo SciFormula:C8H6FNPurity:99%Color and Shape:Pale cream to cream to pale brown to gray, Crystals or powder or crystalline powder or lumpsMolecular weight:135.14Ref: IN-DA0037WV
1g24.00€5g28.00€10g41.00€25g65.00€50g99.00€100g149.00€250g279.00€500g555.00€1kg584.00€5kg2,306.00€10kg4,418.00€5-Fluoroindole
CAS:Formula:C8H6FNPurity:(HPLC) ≥ 98.0%Color and Shape:Off-white to yellow crystalline powderMolecular weight:135.145-Fluoroindole
CAS:5-Fluoroindole is an antimicrobial agent known to inhibit Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) of 4.7 μM. It demonstrates metabolic stability in rat liver microsomes and exhibits antitubercular activity in mice.Formula:C8H6FNColor and Shape:SolidMolecular weight:135.13835-Fluoroindole
CAS:Controlled ProductApplications 5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.
References Richter, J., et al.: J. Am. Chem. Soc., 129, 12857 (2007); Yeung, B., et al.: J. Med. Chem., 53, 5155 (2010);Formula:C8H6FNColor and Shape:NeatMolecular weight:135.145-Fluoro-1H-indole
CAS:5-Fluoro-1H-indoleFormula:C8H6FNPurity:97%Color and Shape:white to beige SolidMolecular weight:135.138345-Fluoroindole
CAS:5-Fluoroindole is a reagent that can be used in organic synthesis. It can be used to synthesize a variety of compounds, including pharmaceuticals and agrochemicals. 5-Fluoroindole is also useful as an intermediate for the synthesis of complex molecules or fine chemicals. 5-Fluoroindole can be used as a building block for the preparation of other chemical compounds. It is a versatile building block with many applications in research and industry.Formula:C8H6FNMolecular weight:135.14 g/mol
