CAS 40034-42-2: Rosoxacin

Description: Rosoxacin is a synthetic antibacterial agent belonging to the class of quinolone antibiotics. It is primarily characterized by its ability to inhibit bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and transcription. This mechanism of action makes Rosoxacin effective against a range of Gram-positive and Gram-negative bacteria. The compound is typically administered orally and is known for its relatively low toxicity profile compared to other antibiotics. Rosoxacin exhibits good bioavailability and is often used in the treatment of various infections, including urinary tract infections and respiratory tract infections. Its chemical structure features a bicyclic core, which is common among quinolones, contributing to its pharmacological properties. Additionally, Rosoxacin has been studied for its potential in treating infections caused by resistant bacterial strains, highlighting its relevance in the context of antibiotic resistance. However, like all antibiotics, its use should be guided by susceptibility patterns to minimize the risk of resistance development.

Formula: C₁₇H₁₄N₂O₃

InChI: InChI=1S/C17H14N2O3/c1-2-19-10-14(17(21)22)16(20)13-4-3-12(9-15(13)19)11-5-7-18-8-6-11/h3-10H,2H2,1H3,(H,21,22)

InChI key: InChIKey=XBPZXDSZHPDXQU-UHFFFAOYSA-N

SMILES: O=C(O)C1=CN(C=2C=C(C=CC2C1=O)C=3C=CN=CC3)CC

Synonyms:

• 1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-3-quinolinecarboxylic acid
• 1-Ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid
• Acrosoxacin
• Eracin
• Eradacil
• Eradacin
• Nsc 146617
• Rosoxacin
• Rosoxacine
• Rosoxacino
• Roxadyl
• Win 35213
• Winuron
• 3-Quinolinecarboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridinyl)-
• 1-ethyl-4-oxo-7-(4-pyridyl)quinoline-3-carboxylic acid

rosoxacin

CAS: 40034-42-2

• Formula: C₁₇H₁₄N₂O₃
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 294.3047

Rosoxacin

CAS: 40034-42-2

• Purity: 99%
• Molecular weight: 294.3g/mol

Rosoxacin-d5

CAS: 40034-42-2

• Formula: C₁₇H₉D₅N₂O₃
• Color and Shape: Neat
• Molecular weight: 299.34

Rosoxacin Hemisulfate

CAS: 40034-42-2

Applications Rosoxacin has shown to have antibacterial activity against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, …

• Formula: C₁₇H₁₄N₂O₃H₂SO₄)
• Color and Shape: Neat
• Molecular weight: 294.30129808

Rosoxacin Potassium Salt (~90%)

CAS: 40034-42-2

Stability Hygroscopic Applications Rosoxacin Potassium Salt is an salt analog of Rosoxacin (R693580), an antibacterial …

• Formula: C₁₇H₁₃KN₂O₃
• Purity: ~90%
• Color and Shape: Neat
• Molecular weight: 332.4

Rosoxacin

CAS: 40034-42-2

Rosoxacin (Acrosoxacin) shows antibacterial activities against a broad spectrum of Gram-negative bacteria including Neisseria gonorrhoeae …

• Formula: C₁₇H₁₄N₂O₃
• Purity: 99.22%
• Color and Shape: Solid
• Molecular weight: 294.3

Rosoxacin Hemisulfate

CAS: 40034-42-2

Rosoxacin hemisulfate (ROX) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. …

• Formula: C₁₇H₁₄N₂O₃•(H₂SO₄)₀
• Purity: Min. 95%
• Molecular weight: 294.3 g/mol