CAS 4009-98-7

(Methoxymethyl)triphenylphosphonium chloride

Description:

(Methoxymethyl)triphenylphosphonium chloride, with the CAS number 4009-98-7, is a quaternary ammonium salt characterized by its triphenylphosphonium cation and a methoxymethyl group. This compound typically appears as a white to off-white solid and is soluble in polar organic solvents. It is known for its role in organic synthesis, particularly in the formation of phosphonium ylides, which are useful intermediates in various reactions, including the Wittig reaction for alkene synthesis. The presence of the methoxymethyl group enhances its reactivity and solubility properties. Additionally, the triphenylphosphonium moiety contributes to its stability and ability to act as a nucleophile. This compound is often handled with care due to its potential toxicity and should be stored in a cool, dry place away from incompatible materials. Overall, (Methoxymethyl)triphenylphosphonium chloride is a valuable reagent in synthetic organic chemistry, facilitating the formation of complex molecular structures.

Formula: C₂₀H₂₀OP·Cl

InChI: InChI=1S/C20H20OP.ClH/c1-21-17-22(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20;/h2-16H,17H2,1H3;1H/q+1;/p-1

InChI key: InChIKey=SJFNDMHZXCUXSA-UHFFFAOYSA-M

SMILES: [P+](COC)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Cl-]

Synonyms:

• (Methoxymethyl)triphenylphosphanium chloride
• Aurora Ka-1153
• Chloro(methoxy)triphenylphosphorane
• Chloro-Methoxy-Triphenyl-Phosphorane
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• MMC
• Methoxymethyl Triphenyl Phosphonium Chloride
• Methoxymethyltriphenyl Phosphoniumchloride
• NSC 49223
• Phosphonium, (methoxymethyl)triphenyl-, chloride
• Phosphonium, (methoxymethyl)triphenyl-, chloride (1:1)
• Phosphorane, Chloromethoxytriphenyl-
• Triphenyl(methoxymethyl)phosphonium chloride
• [(Methyloxy)methyl]triphenylphosphonium chloride
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• (Methoxymethyl)triphenylphosphonium chloride
• Methoxymethyltriphenylphosphanium chloride
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-
• [1aS-(1aa,8b,8aa,8ba)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2,3,4]pyrrolo[1,2-a]indole-4,7-dione
• METHOXYMETHYL-TRIPHENYLPHOSPHONIUM-

(Methoxymethyl)triphenylphosphonium Chloride

CAS: 4009-98-7

Formula: C₂₀H₂₀ClOP

Purity: >99.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 342.80

Ref: 3B-M0828

(Methoxymethyl)triphenylphosphonium chloride

CAS: 4009-98-7

Formula: C₂₀H₂₀ClOP

Purity: 98%

Color and Shape: Solid, Crystalline

Molecular weight: 342.8

Ref: 10-F092547

(Methoxymethyl)triphenylphosphonium chloride, 98+%

CAS: 4009-98-7

(Methoxymethyl)triphenylphosphonium chloride is used as a phase transfer catalyst and in the synthesis of taxol-A fragment. It is widely used in the synthesis of pharmaceutical product cephalotaxine, which is used as an antiviral and antitumor agent. This Thermo Scientific Chemicals brand product

Formula: C₂₀H₂₀ClOP

Purity: 98+%

Color and Shape: White to very pale cream, Powder or crystals or crystalline powder

Molecular weight: 342.80

Ref: 02-A14380

(Methoxymethyl)Triphenylphosphonium Chloride

CAS: 4009-98-7

Formula: C₂₀H₂₀ClOP

Purity: 98%

Color and Shape: Solid

Molecular weight: 342.7990

Ref: IN-DA0032DE

(Methoxymethyl)tris(phenyl)phosphonium chloride

CAS: 4009-98-7

(Methoxymethyl)tris(phenyl)phosphonium chloride

Formula: C₂₀H₂₀OP·Cl

Purity: 98%

Color and Shape: white crystalline solid

Molecular weight: 342.80g/mol

Ref: 54-OR10664

Methoxymethyl triphenylphosphonium chloride

CAS: 4009-98-7

Formula: C₂₀H₂₀ClOP

Color and Shape: White to off-white crystalline powder

Molecular weight: 342.81

Ref: 7W-GK7979

[(Methoxy)methyl]triphenylphosphonium Chloride

CAS: 4009-98-7

Applications [(Methoxy)methyl]triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment.
References Sells, M., et al.: J. Virol., 62, 2836 (1988), Kaneko, S., et al.: J. Clin. Microbiol., 27, 1930 (1989), Baba, Y., et al.: Bioorg. Med. Chem., 13, 5164 (2005), Romero, M., et al.: Antiviral Res., 68, 75 (2005); Hirai, S. et al.: Tetrahedron Lett., 54, 1888 (2013); Xing, P. et al.: Synth., 45, 596 (2013);

Formula: C₂₀H₂₀OP·Cl

Color and Shape: Neat

Molecular weight: 342.80

Ref: TR-M264680

(Methoxymethyl) triphenylphosphonium chloride

CAS: 4009-98-7

Methoxymethyl triphenylphosphonium chloride (MMTPC) is a chemical compound that has been used in vitro as an inhibitor of microbial growth. MMTPC has been shown to be effective against a number of bacterial strains, including methicillin-resistant Staphylococcus aureus and Mycobacterium tuberculosis. This agent inhibits the synthesis of proteins and nucleic acids, which may lead to cell death by inhibiting protein synthesis or by preventing DNA synthesis. MMTPC has been shown to be effective for the treatment of congestive heart failure, coronary heart disease, and autoimmune diseases. It also binds to receptors on cells that are involved in the inflammatory response, such as cytokines and leukocytes.

Formula: C₂₀H₂₀ClOP

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 342.8 g/mol

Ref: 3D-FM34383