CAS 402-45-9

4-(Trifluoromethyl)phenol

Description:

4-(Trifluoromethyl)phenol, also known by its CAS number 402-45-9, is an organic compound characterized by the presence of a trifluoromethyl group (-CF3) attached to a phenolic ring. This compound typically appears as a white to off-white solid and is known for its distinctive properties, including high lipophilicity due to the trifluoromethyl group, which enhances its stability and reactivity. The presence of the hydroxyl (-OH) group on the phenol ring contributes to its acidity and potential for hydrogen bonding, making it a useful intermediate in organic synthesis. It is often employed in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Additionally, 4-(Trifluoromethyl)phenol exhibits unique electronic properties, which can influence its behavior in chemical reactions and interactions with biological systems. Safety considerations include handling it with care, as it may pose health risks upon exposure. Overall, this compound is significant in various chemical applications due to its unique structural features and reactivity.

Formula: C₇H₅F₃O

InChI: InChI=1S/C7H5F3O/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4,11H

InChI key: InChIKey=BAYGVMXZJBFEMB-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(O)C=C1

Synonyms:

• 4-(Trifluoromethyl)phenol
• 4-Hydroxybenxotrifluoride
• 4-Hydroxybenzotrifluoride
• 4-Trifluoromethylphenol
• NSC 88303
• Phenol, 4-(trifluoromethyl)-
• p-Cresol, α,α,α-trifluoro-
• p-Hydroxybenzotrifluoride
• p-Trifluoromethylphenol
• α,α,α-Trifluoro-4-cresol
• α,α,α-Trifluoro-p-cresol

Trifluoro-4-cresol (4-trifluoromethylphenol)

CAS: 402-45-9

Derivatives of phenols or phenol-alcohols, containing only halogen substitutes and their salts, nesoi

Formula: C₇H₅F₃O

Color and Shape: White Dark Yellow Solid

Molecular weight: 162.02925

Ref: 45-1A08620

4-(Trifluoromethyl)phenol

CAS: 402-45-9

4-(Trifluoromethyl)phenol

Formula: C₇H₅F₃O

Purity: 98%

Molecular weight: 162.11

Ref: IN-DG4414

4-(Trifluoromethyl)phenol

CAS: 402-45-9

4-(Trifluoromethyl)phenol

Formula: C₇H₅F₃O

Purity: 95%

Color and Shape: Solid-Crystals

Molecular weight: 162.11

Ref: 54-PC103990

4-Hydroxybenzotrifluoride

CAS: 402-45-9

Formula: C₇H₅F₃O

Molecular weight: 162.11

Ref: 7W-GK2552

4-Hydroxybenzotrifluoride (α-Trifluoro p-Cresol; 4-Trifluoromethylphenol)

CAS: 402-45-9

Formula: C₇H₅F₃O

Color and Shape: White To Off-White Solid

Molecular weight: 162.11

Ref: 4Z-P-578

4-(Trifluoromethyl)phenol

CAS: 402-45-9

4-(Trifluoromethyl)phenol is a useful organic compound for research related to life sciences. The catalog number is T66972 and the CAS number is 402-45-9.

Formula: C₇H₅F₃O

Color and Shape: Solid

Molecular weight: 162.111

Ref: TM-T66972

4-Hydroxybenzotrifluoride

Controlled Product

CAS: 402-45-9

Formula: C₇H₅F₃O

Color and Shape: Neat

Molecular weight: 162.11

Ref: 86-MM0256.05

4-Hydroxybenzotrifluoride

CAS: 402-45-9

Formula: C₇H₅F₃O

Purity: >98.0%(GC)(T)

Color and Shape: White to Yellow to Orange powder to lump

Molecular weight: 162.11

Ref: 3B-H0644

4-(Trifluoromethyl)phenol

Controlled Product

CAS: 402-45-9

Formula: C₇H₅F₃O

Color and Shape: Neat

Molecular weight: 162.11

Ref: 04-C17845820

p-Trifluoromethylphenol

Controlled Product

CAS: 402-45-9

Applications p-Trifluoromethylphenyl is used in the synthesis of P2Y1 antagonists and antithrombotic agents. Also, used in the synthesis of potent myeloid cell leukemia inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chao, H. et al.: J. Med. Chem., 56, 1704, 2013; Friberg, A. et al.: J. Med. Chem., 56, 15 (2013);

Formula: C₇H₅F₃O

Color and Shape: Neat

Molecular weight: 162.11

Ref: TR-T791360

4-(Trifluoromethyl)phenol

CAS: 402-45-9

4-(Trifluoromethyl)phenol is an inorganic acid that is used as a solvent and a chemical intermediate. It has been shown to inhibit the activity of human liver diazonium salt, which is involved in the metabolism of amino acids, fatty acids, and carbohydrates. 4-(Trifluoromethyl)phenol also inhibits the metabolism of propionate by inhibiting the enzyme propionate kinase. The inhibition of this enzyme leads to an accumulation of propionate in urine samples. 4-(Trifluoromethyl)phenol has also been shown to have anti-inflammatory properties. This may be due to its ability to inhibit serotonin reuptake, which causes an increase in serotonin levels in blood platelets and neutrophils, which decreases inflammation caused by these cells.

Formula: C₇H₅F₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 162.11 g/mol

Ref: 3D-FT66959

4-Hydroxybenzotrifluoride

CAS: 402-45-9

Formula: C₇H₅F₃O

Purity: 98%

Color and Shape: Solid

Molecular weight: 162.111

Ref: 10-F001399

4-(trifluoromethyl)phenol

CAS: 402-45-9

Formula: C₇H₅F₃O

Molecular weight: 162.11

Ref: ST-EA-CP-F19048