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CAS 40216-83-9

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4-Hydroxy-L-proline methyl ester hydrochloride

Description:
4-Hydroxy-L-proline methyl ester hydrochloride is a derivative of proline, an amino acid that plays a crucial role in protein synthesis and collagen formation. This compound features a hydroxyl group at the fourth carbon of the proline ring, which contributes to its unique properties. As a methyl ester, it has a methoxy group attached to the carboxylic acid, enhancing its solubility in organic solvents. The hydrochloride form indicates that it is a salt, which typically improves stability and solubility in aqueous solutions. This compound is often utilized in biochemical research and pharmaceutical applications, particularly in studies related to collagen synthesis and as a potential building block in peptide synthesis. Its molecular structure allows for various interactions, making it a valuable compound in medicinal chemistry. Additionally, it may exhibit biological activities, although specific effects would depend on the context of its use and the biological systems involved. Overall, 4-Hydroxy-L-proline methyl ester hydrochloride is a significant compound in both synthetic and biological chemistry.
Formula:C6H11NO3·ClH
InChI:InChI=1S/C6H11NO3.ClH/c1-10-6(9)5-2-4(8)3-7-5;/h4-5,7-8H,2-3H2,1H3;1H/t4-,5+;/m1./s1
InChI key:InChIKey=KLGSHNXEUZOKHH-JBUOLDKXSA-N
SMILES:C(OC)(=O)[C@@H]1C[C@@H](O)CN1.Cl
Synonyms:
  • (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid methyl ester hydrochloride
  • (2S,4R)-Methyl 4-Hydroxypyrrolidine-2-Carboxylate Hydrochloride
  • (4R)-4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
  • 4-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
  • 4-Hydroxy-L-Proline Methyl Ester Hcl
  • 4-Hydroxyproline ester hydrochloride
  • 4-Hydroxyproline methyl ester hydrochloride
  • 4-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline methyl ester hydrochloride
  • <span class="text-smallcaps">L</span>-Hydroxyproline methyl ester hydrochloride
  • <span class="text-smallcaps">L</span>-Proline, 4-hydroxy-, methyl ester, hydrochloride (1:1), (4R)-
  • See more synonyms
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Found 10 products.
  • trans-4-Hydroxy-L-proline Methyl Ester Hydrochloride

    CAS:
    Formula:C6H11NO3·HCl
    Purity:>98.0%(T)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:181.62

    Ref: 3B-H1533

    5g
    38.00€
    25g
    121.00€
  • trans-4-Hydroxy-L-proline methyl ester hydrochloride, 98%

    CAS:
    <p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>
    Formula:C6H12ClNO3
    Purity:98%
    Color and Shape:White, Crystals
    Molecular weight:181.62

    Ref: 02-H51726

    5g
    49.00€
    25g
    144.00€
  • H-Hyp-OMe · HCl

    CAS:
    <p>Bachem ID: 4002341.</p>
    Formula:C6H11NO3·HCl
    Purity:> 99%
    Color and Shape:White
    Molecular weight:181.62

    Ref: 01-4002341

    5g
    90.00€
    25g
    242.00€
  • H-Hyp-OMe.HCl

    CAS:
    Formula:C6H12ClNO3
    Purity:97%
    Color and Shape:Solid
    Molecular weight:181.6174

    Ref: IN-DA003UY3

    1g
    To inquire
    5g
    21.00€
    10g
    20.00€
    25g
    25.00€
    50g
    28.00€
    100g
    43.00€
    500g
    126.00€
  • Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride

    CAS:
    <p>Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride</p>
    Formula:C6H11NO3·ClH
    Purity:≥95%
    Color and Shape: white to off-white solid
    Molecular weight:181.62g/mol

    Ref: 54-OR14759

    5g
    32.00€
    10g
    42.00€
    25g
    64.00€
  • L-4-Hydroxyproline methyl ester hydrochloride

    CAS:
    Formula:C6H11NO3HCl
    Molecular weight:181.62

    Ref: 7W-GM2861

    ne
    To inquire
  • L-4-Hydroxyproline Methyl Ester HCl

    CAS:
    Formula:C6H11NO3·HCl
    Molecular weight:145.16 36.46

    Ref: 4Z-P-166023

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
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    100mg
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  • trans-4-Hydroxy-L-proline Methyl Ester Hydrochloride

    CAS:
    <p>Applications trans-4-Hydroxy-L-proline (H952376) derivative. A natural constituent of animal structural proteins such as collagen and elastin.<br>References Langmaier, F. et al.: Int. J. Cosm. Sci., 24, 273 (2002); Lawrence, C., et al.: Biochem. J., 313, 185 (1996); Mori, H., et al.: J. Bacteriol.; 179, 5677 (1997); Clifton, I., et al.: Eur. J. Biochem., 268, 6625 (2001)<br></p>
    Formula:C6H12ClNO3
    Color and Shape:Neat
    Molecular weight:181.62

    Ref: TR-H952395

    250mg
    86.00€
  • Methyl (2S,4R)-4-hydroxypyrrolidine-2-carboxylate hydrochloride

    CAS:
    Formula:C6H12ClNO3
    Purity:97%
    Color and Shape:Solid, Crystalline Powder or Solid
    Molecular weight:181.62

    Ref: 10-F066958

    1g
    9.00€
    5g
    9.00€
    10g
    12.00€
    1kg
    175.00€
    25g
    12.00€
    100g
    29.00€
    250g
    67.00€
    500g
    97.00€
  • trans-4-Hydroxy-L-proline methyl ester hydrochloride

    CAS:
    <p>Trans-4-hydroxy-L-proline methyl ester hydrochloride is a matrix metalloproteinase inhibitor. It inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen and other proteins in the extracellular matrix. The inhibition of these enzymes leads to a decrease in restenosis, which is the recurrence of artery narrowing after angioplasty or stent placement. Trans-4-hydroxy-L-proline methyl ester hydrochloride has been shown to be effective against chemokine receptors, including CCR5 receptor and chemokines such as TNFα. It also inhibits cytokine production by inhibiting signaling pathways that lead to inflammation and cell proliferation.</p>
    Formula:C6H11NO3·HCl
    Color and Shape:White/Off-White Solid
    Molecular weight:181.62 g/mol

    Ref: 3D-FH24381

    1kg
    607.00€
    2kg
    748.00€
    5kg
    1,085.00€