CAS 405-85-6

4-[(3-fluorobenzyl)oxy]benzoic acid

Description:

4-[(3-Fluorobenzyl)oxy]benzoic acid, with the CAS number 405-85-6, is an organic compound characterized by its aromatic structure and functional groups. It features a benzoic acid moiety, which includes a carboxylic acid (-COOH) group, contributing to its acidic properties. The presence of a 3-fluorobenzyl ether substituent enhances its chemical reactivity and solubility in organic solvents. This compound typically appears as a white to off-white solid and is soluble in polar organic solvents. Its fluorine atom can influence the compound's electronic properties, potentially affecting its interactions in biological systems or its utility in various chemical applications. The compound may be used in pharmaceutical research, particularly in the development of drugs or as an intermediate in organic synthesis. Safety data sheets should be consulted for handling and storage guidelines, as with any chemical substance, to ensure safe laboratory practices.

Formula: C₁₄H₁₁FO₃

InChI: InChI=1/C14H11FO3/c15-12-3-1-2-10(8-12)9-18-13-6-4-11(5-7-13)14(16)17/h1-8H,9H2,(H,16,17)

SMILES: c1cc(cc(c1)F)COc1ccc(cc1)C(=O)O

Synonyms:

• Benzoic Acid, 4-[(3-Fluorophenyl)Methoxy]-
• 4-[(3-Fluorobenzyl)oxy]benzoic acid

Benzoic acid,4-[(3-fluorophenyl)methoxy]-

CAS: 405-85-6

Formula: C₁₄H₁₁FO₃

Purity: 95%

Molecular weight: 246.2337

Ref: IN-DA0076HD

Safinamide Impurity 10

CAS: 405-85-6

Formula: C₁₄H₁₁FO₃

Color and Shape: White To Off-White Solid

Molecular weight: 246.24

Ref: 4Z-S-073012

4-(3-Fluorobenzyloxy)benzoic acid

CAS: 405-85-6

4-(3-Fluorobenzyloxy)benzoic acid

Formula: C₁₄H₁₁FO₃

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 246.23374

Ref: 54-PC10297

4-((3-Fluorobenzyl)oxy)benzoic acid

CAS: 405-85-6

Purity: 98%

Molecular weight: 246.2369995

Ref: 10-F721181

4-[(3-Fluorobenzyl)oxy]benzoic Acid

Controlled Product

CAS: 405-85-6

Applications 4-[(3-Fluorobenzyl)oxy]benzoic acid is a metabolite of Safinamide. Safinamide is a potent and selective MAO-B inhibitor, and is used as an add-on treatment to treat Parkinson’s disease.
References Finberg, J.P.M., et al.: Front Pharmacol., 7, 340-54 (2016);

Formula: C₁₄H₁₁FO₃

Color and Shape: Neat

Molecular weight: 246.234

Ref: TR-F588695

Safinamide Impurity 9

CAS: 405-85-6

Formula: C₁₄H₁₁FO₃

Molecular weight: 246.24

Ref: ST-EA-CP-S15009

NW-1689

CAS: 405-85-6

NW-1689 is a process-related impurity of safinamide mesilate (SAFM), which is a medication used in the treatment of Parkinson's disease (PD). SAFM acts as a highly selective and reversible inhibitor of monoamine oxidase-B (MAO-B) and also blocks sodium and N-type calcium channels. These actions assist in reducing dopamine breakdown and suppressing glutamate release. NW-1689 shares structural similarities with SAFM and exhibits comparable pharmacological effects, making it applicable in Parkinson's disease research.

Formula: C₁₄H₁₁FO₃

Color and Shape: Solid

Molecular weight: 246.23

Ref: TM-TYD-02772