CAS 40615-36-9

4,4′-Dimethoxytrityl chloride

Description:

4,4′-Dimethoxytrityl chloride, with the CAS number 40615-36-9, is a chemical compound commonly used in organic synthesis, particularly in the field of nucleic acid chemistry. It is characterized by its trityl group, which consists of a central carbon atom bonded to three aromatic rings, providing significant steric hindrance and stability. The presence of two methoxy groups enhances its solubility in organic solvents and contributes to its reactivity. As a chlorinated derivative, it serves as a protecting group for hydroxyl functionalities in the synthesis of nucleotides and oligonucleotides, allowing for selective reactions without interference from other functional groups. The compound is typically handled under anhydrous conditions due to its sensitivity to moisture, which can lead to hydrolysis. Its reactivity and stability make it a valuable reagent in synthetic organic chemistry, particularly in the preparation of complex biomolecules. Safety precautions should be observed when handling this compound, as it may pose health risks if inhaled or ingested.

Formula: C₂₁H₁₉ClO₂

InChI: InChI=1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3

InChI key: InChIKey=JBWYRBLDOOOJEU-UHFFFAOYSA-N

SMILES: C(Cl)(C1=CC=C(OC)C=C1)(C2=CC=C(OC)C=C2)C3=CC=CC=C3

Synonyms:

• 1,1'- (Chlorophenylmethylene)bis(4-methoxybenzene)
• 1,1'-(Chlorphenylmethylen)bis[4-methoxybenzol]
• 1,1'-(Clorofenilmetilen)Bis[4-Metoxibenceno]
• 1,1'-[Chloro(Phenyl)Methanediyl]Bis(4-Methoxybenzene)
• 1-[(Chloro)(4-methoxyphenyl)(phenyl)methyl]-4-methoxybenzene
• 1-[Chloro(4-methoxyphenyl)benzyl]-4-methoxybenzene
• 4,4'-Dimethoxy-Triphenylchloromethane
• 4,4'-Dimethoxytriphenyl Chloride
• 4,4-Dimethoxytriphenylmethyl chloride
• 4-[Chloro(4-methoxyphenyl)(phenyl)methyl]-1-methoxybenzene
• Benzene, 1,1'-(chlorophenylmethylene)bis[4-methoxy-
• Bis(4-methoxyphenyl)phenylmethyl chloride
• Chlorobis(4-methoxyphenyl)phenylmethane
• DMT chloride
• DMT-Cl
• DMTrCl
• Di-p-anisylphenylmethyl chloride
• Methyl Chloride, 4,4'-Dimethoxytriphenyl-
• Nsc 89782
• 4,4-Dimethoxytrityl Chloride

4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent]

CAS: 40615-36-9

Formula: C₂₁H₁₉ClO₂

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Light yellow to Light red powder to crystal

Molecular weight: 338.83

Ref: 3B-D1612

4,4'-Dimethoxytrityl chloride, 97%

CAS: 40615-36-9

4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar pr

Formula: C₂₁H₁₉ClO₂

Purity: 97%

Color and Shape: Pale pink to orange, Powder

Molecular weight: 338.83

Ref: 02-A11626

4,4'-Dimethoxytrityl chloride

CAS: 40615-36-9

Formula: C₂₁H₁₉ClO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 338.8274

Ref: IN-DA0033UZ

4,4'-Dimethoxytrityl Chloride

CAS: 40615-36-9

4,4'-Dimethoxytrityl Chloride

Formula: C₂₁H₁₉ClO₂

Purity: 98%

Color and Shape: Light Red. Solid-Crystals

Molecular weight: 338.82736

Ref: 54-OR350109

DMT-Cl

CAS: 40615-36-9

M02870 - DMT-Cl

Formula: C₂₁H₁₉ClO₂

Purity: >98%

Color and Shape: Solid, Powder or Crystalline Powder

Molecular weight: 338.8299865722656

Ref: 10-M02870

4,4''-Dimethoxytritylchloride

CAS: 40615-36-9

Formula: C₂₁H₁₉ClO₂

Purity: ≥ 96.0%

Color and Shape: White to pale yellow, light-red or red-orange powder or crystals

Molecular weight: 338.83

Ref: 7W-GE3209

4,4′-Dimethoxytriphenylmethyl chloride

CAS: 40615-36-9

4,4'-Dimethoxytrityl chloride

Formula: C₂₁H₁₉ClO₂

Purity: 98%

Molecular weight: 338.83

Ref: IN-DG1351

4,4'-Dimethoxytrityl Chloride

Controlled Product

CAS: 40615-36-9

Stability Moisture Sensitive
Applications 4,4'-Dimethoxytrityl Chloride (cas# 40615-36-9) is a compound useful in organic synthesis.

Formula: C₂₁H₁₉ClO₂

Color and Shape: Neat

Molecular weight: 338.83

Ref: TR-D461115

4,4'-Dimethoxytrityl chloride

CAS: 40615-36-9

4,4'-Dimethoxytrityl chloride is a versatile compound used in oligonucleotide synthesis as a protecting group. It selectively reacts with thiol groups, allowing for the selective deprotection of nucleosides. This compound can also be used as a calcium scavenger and has been shown to inhibit the formation of d-glucaric acid, which is involved in the metabolism of triptolide. Additionally, 4,4'-Dimethoxytrityl chloride can react with primary alcohols to form esters, making it useful in organic synthesis. It has also been used as an opioid antagonist and has been shown to enhance the stability of sodium perborate in cosmetic formulations.

Formula: C₂₁H₁₉ClO₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 338.83 g/mol

Ref: 3D-FD02569