CAS 4079-26-9

6,11-dihydrothiochromeno[4,3-b]indole

Description:

6,11-Dihydrothiochromeno[4,3-b]indole is a complex organic compound characterized by its unique bicyclic structure that combines elements of both thiochromene and indole. This compound features a thioether linkage and is known for its potential biological activity, which may include antioxidant and anti-inflammatory properties. The presence of sulfur in its structure contributes to its reactivity and interaction with various biological systems. It is typically synthesized through multi-step organic reactions, often involving cyclization processes. The compound's molecular framework allows for various substitutions, which can influence its chemical behavior and biological activity. As with many organic compounds, its solubility, stability, and reactivity can vary depending on the solvent and environmental conditions. While specific applications may not be widely documented, compounds of this type are often explored in medicinal chemistry for their potential therapeutic effects. Safety and handling precautions should be observed, as with all chemical substances, due to the potential for toxicity or reactivity.

Formula: C₁₅H₁₁NS

InChI: InChI=1/C15H11NS/c1-3-7-13-10(5-1)12-9-17-14-8-4-2-6-11(14)15(12)16-13/h1-8,16H,9H2

SMILES: c1ccc2c(c1)c1CSc3ccccc3c1[nH]2

Synonyms:

• [1]Benzothiopyrano[4,3-b]indole, 6,11-dihydro-
• 6,11-Dihydro-5-Thia-11-Aza-Benzo(A)-Fluorene

PD 146176

CAS: 4079-26-9

Formula: C₁₅H₁₁NS

Purity: 98%

Color and Shape: Solid

Molecular weight: 237.3195

Ref: IN-DA00C0CP

6,11-Dihydrothiochromeno[4,3-B]Indole

CAS: 4079-26-9

6,11-Dihydrothiochromeno[4,3-B]Indole

Purity: 98%

Molecular weight: 237.32g/mol

Ref: 54-OR1022881

PD146176

CAS: 4079-26-9

PD146176

Purity: ≥98%

Molecular weight: 237.32g/mol

Ref: 54-BUP06583

PD 146176

CAS: 4079-26-9

Formula: C₁₅H₁₁NS

Purity: ≥ 98.0%

Color and Shape: White to beige solid

Molecular weight: 237.32

Ref: 7W-GL7866

PD146176

CAS: 4079-26-9

PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.

Formula: C₁₅H₁₁NS

Purity: 98.00%

Color and Shape: Solid

Molecular weight: 237.32

Ref: TM-T7530

PD-146176

Controlled Product

CAS: 4079-26-9

Applications PD-146176 is a potent and selective 15-LO inhibitor.

Formula: C₁₅H₁₁NS

Color and Shape: Neat

Molecular weight: 237.32

Ref: TR-P218293

PD146176

CAS: 4079-26-9

PD146176 is a potential anti-cancer compound that inhibits the tumor necrosis factor (TNF) receptor. PD146176 is a small molecule inhibitor of TNF signaling and has been shown to reduce atherosclerotic lesion size in mice. The drug also protects against neuronal death induced by an inflammatory stimulus, such as toll-like receptor 4 (TLR4) agonists. It has been demonstrated to have synergistic activity with other compounds in experiments using miapaca-2 cells and has been shown to inhibit cancer cell growth in culture and in an experimental model. PD146176 may be a target for the development of new drugs for the treatment of various diseases, including bowel disease and cancer.

Formula: C₁₅H₁₁NS

Purity: Min. 95%

Molecular weight: 237.32 g/mol

Ref: 3D-EAA07926