CAS 410536-97-9: Sirtinol

Description: Sirtinol is a small molecule that acts as an inhibitor of sirtuin enzymes, particularly SIRT1, which are involved in various cellular processes including aging, metabolism, and stress response. It is classified as a hydroxamic acid derivative and is known for its potential role in modulating cellular pathways related to longevity and disease. Sirtinol has been studied for its effects on promoting apoptosis in cancer cells and its potential neuroprotective properties. The compound is typically characterized by its ability to interact with the NAD+-dependent deacetylase activity of sirtuins, thereby influencing gene expression and cellular metabolism. In terms of physical properties, Sirtinol is usually presented as a solid at room temperature, with solubility in organic solvents. Its chemical structure includes functional groups that contribute to its biological activity, making it a subject of interest in pharmacological research. However, further studies are needed to fully understand its therapeutic potential and safety profile in clinical applications.

Formula: C₂₆H₂₂N₂O₂

InChI: InChI=1S/C26H22N2O2/c1-18(19-9-3-2-4-10-19)28-26(30)22-13-7-8-14-24(22)27-17-23-21-12-6-5-11-20(21)15-16-25(23)29/h2-18,29H,1H3,(H,28,30)

InChI key: InChIKey=UXJFDYIHRJGPFS-UHFFFAOYSA-N

SMILES: O=C(NC(C=1C=CC=CC1)C)C=2C=CC=CC2N=CC3=C(O)C=CC=4C=CC=CC43

Synonyms:

• 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide
• 2-{[(2-oxonaphthalen-1(2H)-ylidene)methyl]amino}-N-[(1R)-1-phenylethyl]benzamide
• Benzamide, 2-[[(2-hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)-
• S 2804
• Sirtinol

SIRTINOL

CAS: 410536-97-9

• Formula: C₂₆H₂₂N₂O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 394.4651

Sirtinol

CAS: 410536-97-9

• Purity: ≥98%
• Molecular weight: 394.47g/mol

Sirtinol

CAS: 410536-97-9

• Formula: C₂₆H₂₂N₂O₂
• Purity: ≥ 98%
• Color and Shape: Off-white to yellow solid
• Molecular weight: 394.5

Sirtinol

CAS: 410536-97-9

Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).

• Formula: C₂₆H₂₂N₂O₂
• Purity: 99.52% - 99.96%
• Color and Shape: Solid
• Molecular weight: 394.47

Sirtinol

CAS: 410536-97-9

M02526 - Sirtinol

• Formula: C₂₆H₂₂N₂O₂
• Purity: >95%
• Color and Shape: Solid
• Molecular weight: 394.4739990234375

Sirtinol

CAS: 410536-97-9

Applications Sirtinol is a known inhibitor of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5 and …

• Formula: C₂₆H₂₂N₂O₂
• Color and Shape: Neat
• Molecular weight: 394.465

Sirtinol

CAS: 410536-97-9

Sirtinol is an experimental drug that has been shown to have antioxidative properties and is …

• Formula: C₂₆H₂₂N₂O₂
• Purity: Min. 95%
• Molecular weight: 394.47 g/mol