CAS 41575-94-4

Carboplatin

Description:

Carboplatin is a platinum-based chemotherapy drug primarily used in the treatment of various cancers, including ovarian cancer, testicular cancer, and bladder cancer. It is a second-generation platinum compound, structurally related to cisplatin but with a different ligand, which enhances its therapeutic profile and reduces certain side effects. Carboplatin is characterized by its ability to form DNA cross-links, leading to the inhibition of DNA replication and ultimately triggering apoptosis in cancer cells. Its solubility in water allows for intravenous administration, and it is typically given in cycles to maximize efficacy while minimizing toxicity. Common side effects include myelosuppression, nausea, vomiting, and renal toxicity, although these are generally less severe compared to cisplatin. The drug's effectiveness is often influenced by the presence of specific biomarkers in tumors, and it is frequently used in combination with other chemotherapeutic agents to enhance treatment outcomes. Carboplatin's mechanism of action and its relatively favorable side effect profile make it a valuable option in oncological therapies.

Formula: C₆H₁₂N₂O₄Pt

InChI: InChI=1/C6H8O4.2H2N.Pt/c7-4(8)6(5(9)10)2-1-3-6;;;/h1-3H2,(H,7,8)(H,9,10);2*1H2;/q;2*-1;+4/p-2/rC6H10N2O4Pt/c7-13(8)11-4(9)6(2-1-3-6)5(10)12-13/h1-3,7-8H2

InChI key: InChIKey=OLESAACUTLOWQZ-UHFFFAOYSA-L

SMILES: O=C1C2(C(=O)[O-][Pt+2]([NH3])([NH3])[O-]1)CCC2

Synonyms:

• (SP-4-2)-Diammine[1,1-cyclobutanedicarboxylato(2-)-κO,κO′′]platinum
• 1,1-Cyclobutanedicarboxylic acid, platinum complex
• Carbomedac
• Carboplatin
• Carboplatinum
• Carbosin
• Cbdca
• Cycloplatin
• Diammin[cyclobutan-1,1-dicarboxylato(2-)-O,O']platin
• Jm 8
• Nsc 201345
• Nsc 241240
• Paraplat
• Paraplatin
• Platinum, diammine[1,1-cyclobutanedicarboxylato(2-)-κO,κO'']-, (SP-4-2)-
• Platinum, diammine[1,1-cyclobutanedicarboxylato(2-)]-, (SP-4-2)-
• Ribocarbo L
• cis-Diammine(1,1-cyclobutanedicarboxylato)platinum
• cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
• cis-Diammine(cyclobutane-1,1-dicarboxylate-O,O′)platinum(II)
• cis-Diammine[1,1-cyclobutanedicarboxylato(2-)]platinum
• cis-Diammineplatinum 1,1-cyclobutanedicarboxylate
• diamino[ciclobutano-1,1-dicarboxilato(2-)-O,O']platino
• diammine[cyclobutane-1,1-dicarboxylato(2-)-O,O']platine
• diammine[cyclobutane-1,1-dicarboxylato(2-)-O,O']platinum
• diamino[cyclobutane-1,1-dicarboxylato(2-)-kappa~2~O~1~,O~1~]platinum
• 1,1-Cyclobutanedicarboxylate diamine platinum(II)
• cis-(1,1-Cyclobutanedicarboxylato)diamineplatinum(II)
• 1,1-Cyclobutanedicarboxylatodiammineplatinum
• cyclobutane-1,1-dicarboxylic acid - platinum ammoniate (1:1:2)
• Platinum, diammine[1,1-cyclobutanedi(carboxylato-κO)(2-)]-, (SP-4-2)-
• platinum(2+) azanide cyclobutane-1,1-dicarboxylic acid (1:2:1)
• 6,8-dioxa-7$l^{2}-platinaspiro[3.5]nonane-5,9-dione
• ammonia
• 1,1-cyclobutanedicarboxylic acid, platinum(2+) salt (1:1), diammoniate
• diammine(1,1-cyclobutanedicarboxylato)-platinum(I
• Platinum, diamine(1,1-cyclobutanedicarboxylato(2-)-O,O')-,(SP-4-2)-
• cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II)
• 1-cyclobutanedicarboxylato)diammine-(cis-platinum(ii
• 1-cyclobutanedicarboxylato(2-)-o,o’)-diammine((sp-4-2)-platinu
• Carboplatin usp25
• (SP-4-2)-Diamimine[1,1-cyclobutanedi(carboxylato-kO)(2-)]platinum
• JM-8：NSC-241240
• DIAMMINE(1,1-CYCLOBUTANEDICARBOXYLATO)PLATINUM(II)
• CIS-DIAMMINE[1,1-CYCLOBUTANE-DICARBOYLATO]PLATINUM
• CIS-DIAMMINE-[1,1-CYCLOBUTANE-DICARBOXYLATO]PLATIN
• PARAPLATIN (CARBOPLATIN)
• (SP-4-2)-Diamrnine[1，1-cyclobutanedicarboxylato(2-)-O，O’]platinuln
• 1,1-CYCLOBUTANEDICARBOXYLATODIAMMINEPLATINUM(II) CARBOPLATIN
• CIS-DIAMMINE[1,1-CYCLOBUTANE-DICARBOXYLATO] PLATINUM
• CarboplatinUsp24
• diammine-1,1-cyclobutanedicarboxylateplatinumi
• Ercar
• 1,1-cyclobutanedicarboxylatediammineplatinum(ii)
• CarboplatinUsp28
• Carboplatin (100 mg)
• CARBONPLATIN
• 1,1-CYCLOBUTANEDICARBOXYLATODIAMMINEPLATINUM(II)
• CARBOPLATIN (DIAMMINE(1,1-CYCLOBUTANEDICARBOXYLATO)PLATINUM(II))
• 1,1-Cyclobutanedicarboxylatodiammineplatinum(II),99%CARBOPLATIN
• 1,1-cyclobutanedicarboxylate diammine platinum
• SP-4-2)-Diammine[1,1-cyclobutanedicar-boxylato-(2-)O,O’]platinum
• CIS-DIAMINE(1,1-CYCLOBUTANEDICARBOXYLATO)PLATINUM
• cis-(1,1-cyclobutanedicarboxylato)diammineplatinum
• cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(ii)
• diammine(1,1-cyclobutanedicarboxylato)platinum
• Platinum, diammine1,1-cyclobutanedi(carboxylato-.kappa.O)(2-)-, (SP-4-2)-
• 1,1-CYCLOBUTANEDICARBOXYLATODIAMMINEPLATINUM(II), 99% USP CARBOPLATIN
• Carboplatin/cis-DiaMMine[1,1 cyclobutane dicarboxylato] platinuM
• Carboplatin99%

Carboplatin

CAS: 41575-94-4

Carboplatin is primarily used as an antitumor agent.Carboplatin is widely utilized as a chemotherapy drug to treat various types of cancer. It belongs to the group of platinum-based antineoplastic agents to interfere in DNA (deoxyribonucleic acid) repair. It is applied in combination other medicatio

Formula: C₆H₁₂N₂O₄Pt

Color and Shape: White to off-white, Powder

Molecular weight: 371.26

Ref: 02-J60433

Carboplatin

CAS: 41575-94-4

Carboplatin

Formula: C₆H₁₂N₂O₄Pt

Purity: 99.8%

Color and Shape: White To Off-White

Molecular weight: 371.0445

Ref: 47-711

Carboplatin

CAS: 41575-94-4

Inorganic or organic compounds of precious metals, whether or not chemically defined; amalgrams of precious metals, nesoi

Formula: C₆H₁₂N₂O₄Pt

Color and Shape: White Powder

Molecular weight: 371.0445

Ref: 45-1096407

Carboplatin

CAS: 41575-94-4

Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.

Formula: C₆H₁₂N₂O₄Pt

Purity: 98% - 99.72%

Color and Shape: White Crystalline Powder

Molecular weight: 371.25

Ref: TM-T1058

Carboplatin

CAS: 41575-94-4

Carboplatin

Formula: C₆H₁₂N₂O₄Pt

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 371.25

Ref: 54-BUP16123

Carboplatin

CAS: 41575-94-4

Formula: C₆H₁₂N₂O₄Pt

Purity: ≥ 98.0% (anhydrous basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 371.25

Ref: 7W-GA9420

Carboplatin

CAS: 41575-94-4

Formula: C₆H₁₂N₂O₄Pt

Color and Shape: Off-White Solid

Molecular weight: 371.26

Ref: 4Z-C-10701

Carboplatin

CAS: 41575-94-4

Formula: C₆H₁₂N₂O₄Pt

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 371.26

Ref: 3B-C2043

Platinum(II) diammine cyclobutane dicarboxylate, 99.95% (metals basis)

CAS: 41575-94-4

Ref: 7W-GX5537

Carboplatin-d4

Controlled Product

CAS: 41575-94-4

Stability Hygroscopic
Applications Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic.
References Harland, S.J., et al.: Cancer Res., 44, 1693 (1984), Smith, I.E., et al.: Cancer Treat. Rep., 69, 43 (1985), Lygidakis, N.J., et al.: Interferon Cytokine Res., 15, 467 (1995),

Formula: C₆H₈D₄N₂O₄Pt

Color and Shape: Neat

Molecular weight: 375.27

Ref: TR-C177502

Carboplatin

CAS: 41575-94-4

Applications Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic.
References Harland, S.J., et al.: Cancer Res., 44, 1693 (1984), Smith, I.E., et al.: Cancer Treat. Rep., 69, 43 (1985), Lygidakis, N.J., et al.: Interferon Cytokine Res., 15, 467 (1995),

Formula: C₆H₁₂N₂O₄Pt

Color and Shape: Neat

Molecular weight: 371.25

Ref: TR-C177500

Carboplatin - Bio-X ™

CAS: 41575-94-4

Carboplatin is an antineoplastic alkylating agent that is used in the treatment of ovarian cancer. This drug attaches alkyl groups to nucleotides leading to the formation of monoadducts. Carboplatin’s main mechanism of action is preventing DNA strands from separating for synthesis and transcription.

Formula: C₆H₁₂N₂O₄Pt

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 371.25 g/mol

Ref: 3D-BC164284

Carboplatin

CAS: 41575-94-4

Platinum-based anti-cancer agent

Formula: C₆H₁₂N₂O₄Pt

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 371.25 g/mol

Ref: 3D-FC01462

1,1-Cyclobutanedicarboxylatodiammineplatinum

CAS: 41575-94-4

Formula: C₆H₁₂N₂O₄Pt

Purity: 97.0%

Molecular weight: 371.256

Ref: 10-F036511

Carboplatin

CAS: 41575-94-4

Formula: C₆H₁₂N₂O₄Pt

Molecular weight: 371.25

Ref: ST-EA-CP-C56000

Carboplatin RS

CAS: 41575-94-4

Color and Shape: White

Ref: 2K-1040500021