CAS 415903-37-6
:Grapiprant
Description:
Grapiprant is a non-steroidal anti-inflammatory drug (NSAID) primarily used in veterinary medicine, particularly for the management of pain and inflammation associated with osteoarthritis in dogs. It functions as a selective antagonist of the EP4 receptor, which is a subtype of the prostaglandin E2 receptor. By inhibiting this receptor, Grapiprant effectively reduces pain and inflammation without the gastrointestinal side effects commonly associated with traditional NSAIDs. The chemical structure of Grapiprant includes a pyrimidine ring, contributing to its unique pharmacological profile. It is administered orally and is characterized by its relatively high bioavailability and a favorable safety profile in dogs. Grapiprant's mechanism of action distinguishes it from other NSAIDs, making it a valuable option for managing chronic pain in veterinary patients. As with any medication, it is essential to follow veterinary guidance regarding dosage and administration to ensure the safety and well-being of the animal.
Formula:C26H29N5O3S
InChI:InChI=1S/C26H29N5O3S/c1-5-24-29-25-19(4)28-18(3)16-23(25)31(24)21-10-8-20(9-11-21)14-15-27-26(32)30-35(33,34)22-12-6-17(2)7-13-22/h6-13,16H,5,14-15H2,1-4H3,(H2,27,30,32)
InChI key:InChIKey=HZVLFTCYCLXTGV-UHFFFAOYSA-N
SMILES:C(C)C=1N(C=2C(N1)=C(C)N=C(C)C2)C3=CC=C(CCNC(NS(=O)(=O)C4=CC=C(C)C=C4)=O)C=C3
Synonyms:- AAT 007
- 2-Ethyl-4,6-dimethyl-1-[4-[2-[[[[(4-methylphenyl)sulfonyl]amino]carbonyl]amino]ethyl]phenyl]-1H-imidazo[4,5-c]pyridine
- CJ 023423
- N-((4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenethyl)carbamoyl)-4-methylbenzenesulfonamide
- 2-Ethyl-4,6-dimethyl-1-[4-[2-[[[[(4-methylphenyl)sulfonyl]amino]carbonyl]amino]ethyl]phenyl]-1H-imidazo[4,5-c]pyridine
- N-[[[2-[4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methylbenzenesulfonamide
- Benzenesulfonamide, N-[[[2-[4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]amino]carbonyl]-4-methyl-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.
N-((4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenethyl)carbamoyl)-4-methylbenzenesulfonamide
CAS:Formula:C26H29N5O3SPurity:%Color and Shape:SolidMolecular weight:491.6052Ref: IN-DA00C6L9
1gTo inquire1mg50.00€5mg50.00€10mg65.00€25mg124.00€50mg187.00€100mg215.00€250mg363.00€Grapiprant
CAS:N-((4-(2-Ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenethyl)carbamoyl)-4-methylbenzenesulfonamideFormula:C26H29N5O3SPurity:98+%Molecular weight:491.61Grapiprant
CAS:Grapiprant (AAT-007) is a selective EP4 receptor antagonist.Formula:C26H29N5O3SPurity:99.45% - 99.84%Color and Shape:White SolidMolecular weight:491.61CJ-023423
CAS:Applications CJ-023423 is a potent and selective antagonist of E prostanoid 4 (EP4) receptor.
References Babev, V.R., et al.: Cell Metab. 8, 492 (2008; Li, M. et al.: Int Orthop., 31, 767 (2007)Formula:C26H29N5O3SColor and Shape:NeatMolecular weight:491.61CJ-023423 Hydrochloride Salt, Hydrate
CAS:Controlled ProductFormula:C26H29N5O3S•x(HCl)y(H2O)Color and Shape:NeatMolecular weight:491.6136461802CJ-023423 Hydrochloride Salt, Hydrate
CAS:CJ-023423 Hydrochloride Salt, Hydrate is a nonsteroidal anti-inflammatory drug (NSAID) that binds to the prostacyclin receptor. CJ-023423 Hydrochloride Salt, Hydrate has been shown to be effective in treating pain in animal models and clinical trials. It also appears to have a low incidence of gastrointestinal side effects. The crystalline form of CJ-023423 Hydrochloride Salt, Hydrate is currently not available for sale.Formula:C26H29N5O3S•(HCl)x•(H2O)yPurity:Min. 95%Molecular weight:491.61 g/mol
![N-((4-(2-ethyl-4,6-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl)phenethyl)carbamoyl)-4-methylbenzenesulf…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00C6L9.jpg&w=3840&q=75)
