CAS 41600-13-9

N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-gamma-glutamylglutamic acid

Description:

N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-gamma-glutamylglutamic acid, with CAS number 41600-13-9, is a complex organic compound characterized by its structure, which includes a pteridine moiety, an amino acid sequence, and a benzoyl group. This compound is notable for its potential applications in biochemistry and medicinal chemistry, particularly in the context of drug design and delivery systems. The presence of the pteridine ring suggests possible interactions with biological systems, especially in relation to folate metabolism and enzyme inhibition. The amino acid components, specifically the gamma-glutamyl and glutamic acid residues, may contribute to its solubility and reactivity, influencing its pharmacokinetic properties. Additionally, the compound's intricate structure may allow for specific binding interactions with target proteins or enzymes, making it a candidate for further research in therapeutic applications. Overall, its unique combination of functional groups and structural features positions it as a compound of interest in the fields of pharmacology and biochemistry.

Formula: C₂₅H₂₉N₉O₈

InChI: InChI=1/C25H29N9O8/c1-34(11-13-10-28-21-19(29-13)20(26)32-25(27)33-21)14-4-2-12(3-5-14)22(38)31-16(24(41)42)6-8-17(35)30-15(23(39)40)7-9-18(36)37/h2-5,10,15-16H,6-9,11H2,1H3,(H,30,35)(H,31,38)(H,36,37)(H,39,40)(H,41,42)(H4,26,27,28,32,33)

SMILES: CN(Cc1cnc2c(c(N)[nH]c(=N)n2)n1)c1ccc(cc1)C(=O)NC(CCC(=NC(CCC(=O)O)C(=O)O)O)C(=O)O

Methotrexate Diglutamate

CAS: 41600-13-9

Methotrexate Diglutamate

Purity: ≥98%

Molecular weight: 583.55g/mol

Ref: 54-BUP00962

Methotrexate Diglutamate

CAS: 41600-13-9

Formula: C₂₅H₂₉N₉O₈

Molecular weight: 583.56

Ref: 4Z-M-7020

Methotrexate Diglutamate

CAS: 41600-13-9

Methotrexate Diglutamate Small molecule compound present in the liver that acts as a partially purified human dihydrofolate reductase inhibitor.

Formula: C₂₅H₂₉N₉O₈

Purity: 98.51%

Color and Shape: Solid

Molecular weight: 583.55

Ref: TM-T25886

Methotrexate-d3 Diglutamate Trifluoroacetate

Controlled Product

CAS: 41600-13-9, 432545-63-6

Applications Methotrexate-d3 Diglutamate is the isotope labelled analog of Methotrexate Diglutamate (M260720); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)

Formula: C₂₅H₂₆D₃N₉O₈•x(C₂HF₃O₂)•xH₂SO₄

Color and Shape: Neat

Molecular weight: 586.5811402981

Ref: TR-M260722

Methotrexate Diglutamate Trifluoroacetate

Controlled Product

CAS: 41600-13-9

Stability Hygroscopic
Applications Methotrexate Diglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)

Formula: C₂₅H₂₉N₉O₈xC₂HF₃O₂

Color and Shape: Neat

Molecular weight: 583.55

Ref: TR-M260720