CAS 41600-14-0

N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-gamma-glutamyl-L-gamma-glutamyl-L-glutamic acid

Description:

N-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-L-gamma-glutamyl-L-gamma-glutamyl-L-glutamic acid, with CAS number 41600-14-0, is a complex organic compound characterized by its multi-functional structure. It features a pteridine moiety, which is indicative of its potential biological activity, particularly in relation to folate metabolism and cellular processes. The presence of multiple glutamic acid residues suggests that it may play a role in peptide interactions and could be involved in various biochemical pathways. This compound is likely to exhibit solubility in polar solvents due to its amino acid components, and its structure may confer specific binding properties to biological targets. Additionally, the presence of amino groups indicates potential for protonation under physiological conditions, which could influence its reactivity and interaction with other biomolecules. Overall, this compound's intricate structure suggests it may have applications in medicinal chemistry, particularly in the development of targeted therapies or as a biochemical probe.

Formula: C₃₀H₃₆N₁₀O₁₁

InChI: InChI=1/C30H36N10O11/c1-40(13-15-12-33-25-23(34-15)24(31)38-30(32)39-25)16-4-2-14(3-5-16)26(45)37-19(29(50)51)7-10-21(42)35-17(27(46)47)6-9-20(41)36-18(28(48)49)8-11-22(43)44/h2-5,12,17-19H,6-11,13H2,1H3,(H,35,42)(H,36,41)(H,37,45)(H,43,44)(H,46,47)(H,48,49)(H,50,51)(H4,31,32,33,38,39)/t17-,18-,19-/m0/s1

SMILES: CN(Cc1cnc2c(c(N)[nH]c(=N)n2)n1)c1ccc(cc1)C(=O)N[C@@H](CCC(=N[C@@H](CCC(=N[C@@H](CCC(=O)O)C(=O)O)O)C(=O)O)O)C(=O)O

Methotrexate Triglutamate

CAS: 41600-14-0

Methotrexate Triglutamate

Purity: ≥98%

Molecular weight: 712.67g/mol

Ref: 54-BUP00963

Methotrexate Triglutamate

CAS: 41600-14-0

Methotrexate Triglutamate (MTXPG3) has potential anti-inflammatory activity and can be used to study arthritis and lupus erythematosus.

Formula: C₃₀H₃₆N₁₀O₁₁

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 712.67

Ref: TM-T25887

Methotrexate Triglutamate Trifluoroacetate

CAS: 41600-14-0

Formula: C₃₀H₃₆N₁₀O₁₁·C₂HF₃O₂

Molecular weight: 712.67

Ref: 4Z-M-7022

Methotrexate-d3 Triglutamate Trifluoroacetate

Controlled Product

CAS: 41600-14-0, 432545-63-6

Stability Hygroscopic
Applications Methotrexate-d3 Triglutamate is the isotope labelled analog of Methotrexate Triglutamate (M260725); a metabolite of Methotrexate (M260675) which is a folic acid antagonist, antineoplastic, and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)

Formula: C₃₀H₃₃D₃N₁₀O₁₁(C₂HF₃O₂)x

Color and Shape: Neat

Molecular weight: 715.69

Ref: TR-M260727

Methotrexate Triglutamate Trifluoroacetate

Controlled Product

CAS: 41600-14-0

Applications Methotrexate Triglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)

Formula: C₃₀H₃₆N₁₀O₁₁xC₂HF₃O₂

Color and Shape: Neat

Molecular weight: 712.67

Ref: TR-M260725