CAS 41964-07-2

5-(3-Methylphenoxy)-2(1H)-pyrimidinone

Description:

5-(3-Methylphenoxy)-2(1H)-pyrimidinone, with the CAS number 41964-07-2, is a chemical compound that features a pyrimidinone core substituted with a 3-methylphenoxy group. This structure suggests that it possesses both aromatic and heterocyclic characteristics, which can influence its chemical reactivity and biological activity. The presence of the pyrimidinone moiety indicates potential applications in medicinal chemistry, as pyrimidine derivatives are often explored for their pharmacological properties. The 3-methylphenoxy substituent may enhance lipophilicity, potentially affecting the compound's solubility and permeability. Additionally, the compound may exhibit specific interactions with biological targets, making it of interest in drug discovery and development. Its synthesis and characterization would typically involve standard organic chemistry techniques, and its properties can be further elucidated through spectroscopic methods. Overall, this compound represents a class of organic molecules that could have implications in various fields, including pharmaceuticals and agrochemicals.

Formula: C₁₁H₁₀N₂O₂

InChI: InChI=1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)

InChI key: InChIKey=HJQILFPVRNHTIG-UHFFFAOYSA-N

SMILES: O(C1=CC(C)=CC=C1)C2=CNC(=O)N=C2

Synonyms:

• 2(1H)-Pyrimidinone, 5-(3-methylphenoxy)-
• 5-(3-Methylphenoxy)-2(1H)-pyrimidinone
• 5-(3-methylphenoxy)pyrimidin-2(1H)-one
• 5-(m-Tolyloxy)-2(1H)-pyrimidinone
• Cp 26154
• Mlr 1023
• NSC 314335
• Unii-Mu3Jd8E9Is
• Tolimidone

TOLIMIDONE

CAS: 41964-07-2

Formula: C₁₁H₁₀N₂O₂

Purity: 98%

Molecular weight: 202.2093

Ref: IN-DA00C9PY

Tolimidone

CAS: 41964-07-2

Tolimidone

Purity: ≥98%

Molecular weight: 202.21g/mol

Ref: 54-BUP10583

Tolimidone

CAS: 41964-07-2

Formula: C₁₁H₁₀N₂O₂

Molecular weight: 202.21

Ref: 4Z-T-467001

Tolimidone

CAS: 41964-07-2

Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.

Formula: C₁₁H₁₀N₂O₂

Purity: 99.85% - 99.85%

Color and Shape: Solid

Molecular weight: 202.21

Ref: TM-T6896

TOLIMIDONE

CAS: 41964-07-2

Purity: 98%

Molecular weight: 202.2129974

Ref: 10-F803265

Tolimidone

Controlled Product

CAS: 41964-07-2

Applications Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.
References Ochman, A.R. et al.: J. Pharmacol. Exp. Ther., 342, 23 (2012); Saporito, M.S. et al.: J. Pharmacol. Exp. Ther., 342, 15 (2012);

Formula: C₁₁H₁₀N₂O₂

Color and Shape: Neat

Molecular weight: 202.209

Ref: TR-T535340

Tolimidone

CAS: 41964-07-2

Tolimidone is an enzyme inhibitor that binds to the active site of the enzyme HMG-CoA reductase. It inhibits the synthesis of cholesterol, leading to reduced levels of LDL and VLDL cholesterol. Tolimidone has also been shown to reduce plasma glucose and pro-inflammatory cytokines. This drug is currently being investigated as a potential treatment for high cholesterol and diabetes. The effective dose of tolimidone is not yet known, but it has been shown in vivo that it can lower cholesterol levels by up to 60%.

Formula: C₁₁H₁₀N₂O₂

Purity: Min. 95%

Molecular weight: 202.21 g/mol

Ref: 3D-RBA96407