CAS 42123-27-3

Tetradehydropodophyllotoxin

Description:

Tetradehydropodophyllotoxin is a chemical compound derived from the plant Podophyllum peltatum, commonly known as the mayapple. It belongs to the class of compounds known as lignans and is characterized by its complex polycyclic structure. This substance exhibits notable biological activity, particularly as an antitumor agent, and has been studied for its potential in cancer therapy due to its ability to inhibit cell division. Tetradehydropodophyllotoxin functions by interfering with the mitotic spindle formation, thereby preventing cancer cells from proliferating. Additionally, it has shown antiviral properties, particularly against certain types of viruses. The compound is typically found in a crystalline form and is soluble in organic solvents. Its pharmacological profile includes a range of effects, making it a subject of interest in medicinal chemistry and drug development. However, like many bioactive compounds, it may also exhibit toxicity, necessitating careful evaluation in therapeutic contexts. Overall, tetradehydropodophyllotoxin represents a significant compound in the exploration of natural products for medicinal applications.

Formula: C₂₂H₁₈O₈

Synonyms:

• Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one, 9-hydroxy-5-(3,4,5-trimethoxyphenyl)-
• Inhibitor,Fungal,Tetradehydropodophyllotoxin,inhibit
• Tetradehydropodophyllotoxin

Tetradehydropodophyllotoxin

CAS: 42123-27-3

Tetradehydropodophyllotoxin

Purity: ≥95%

Molecular weight: 410.37g/mol

Ref: 54-BUP00910

Dehydropodophyllotoxin

CAS: 42123-27-3

Formula: C₂₂H₁₈O₈

Purity: 95%~99%

Molecular weight: 410.378

Ref: BP-BP4756

Podophyllotoxin Impurity 3

CAS: 42123-27-3

Formula: C₂₂H₁₈O₈

Molecular weight: 410.38

Ref: 4Z-P-122003

Tetradehydropodophyllotoxin

CAS: 42123-27-3

Tetradehydropodophyllotoxin (Dehydropodophyllotoxin) has anti-tumor activity.

Formula: C₂₂H₁₈O₈

Purity: 96.95% - 98.22%

Color and Shape: Solid

Molecular weight: 410.37

Ref: TM-TN2356

Dehydropodophyllotoxin

CAS: 42123-27-3

Dehydropodophyllotoxin is a lignan compound, which is derived from the roots and rhizomes of the plant genus Podophyllum. It exhibits its activity primarily as an inhibitor of microtubule assembly. Microtubules are essential components of the cell cytoskeleton, playing a critical role in cell division and intracellular transport. By interfering with microtubule dynamics, dehydropodophyllotoxin disrupts mitosis, leading to cell cycle arrest and potential apoptosis in rapidly dividing cancer cells.

Formula: C₂₂H₁₈O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 410.37 g/mol

Ref: 3D-FD74071

Tetradehydropodophyllotoxin

Controlled Product

CAS: 42123-27-3

Applications Tetradehydropodophyllotoxin is a aryl-naphthalene lignans that was shown to exhibit anticancer activities.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hui, J., et al.: Med. Chem. Res., 21, 3994 (2012); Tian, H., et al.: Brit. J. Pharmacol., 150, 321 (2007); Ter, Harr, E., et al.: Bioorg. Med. Chem., 4, 1659 (1996);

Formula: C₂₂H₁₈O₈

Color and Shape: Neat

Molecular weight: 410.37

Ref: TR-T291445