CAS 42397-65-9

1,8-Dinitropyrene

Description:

1,8-Dinitropyrene is an organic compound classified as a polycyclic aromatic hydrocarbon (PAH) with the chemical formula C12H8N2O4. It features two nitro groups (-NO2) attached to the pyrene structure, specifically at the 1 and 8 positions. This compound is typically characterized by its yellow crystalline appearance and is known for its potential environmental and health impacts. 1,8-Dinitropyrene is considered a mutagen and has been studied for its carcinogenic properties, particularly in relation to its ability to form DNA adducts. It is relatively insoluble in water but soluble in organic solvents, which influences its behavior in environmental contexts. The compound is often associated with combustion processes, such as those occurring in vehicle emissions and industrial activities, leading to its presence in air and soil. Due to its toxicological profile, 1,8-dinitropyrene is subject to regulatory scrutiny, and research continues to assess its risks and mechanisms of action in biological systems.

Formula: C₁₆H₈N₂O₄

InChI: InChI=1S/C16H8N2O4/c19-17(20)13-7-3-9-1-2-10-4-8-14(18(21)22)12-6-5-11(13)15(9)16(10)12/h1-8H

InChI key: InChIKey=BLYXNIHKOMELAP-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=C2C3=C4C(=C(N(=O)=O)C=CC4=CC=C3C=C1)C=C2

Synonyms:

• 1,8-Dinitropyrene [Nitroarenes]
• Brn 3413165
• Ccris 2585
• Pyrene, 1,8-dinitro-
• 1,8-Dinitropyrene
• 1,8-DINITROPYRENE (100UG/ML IN TOLUENE)
• 1,8-Dinitropyrene@100 μg/mL in Toluene
• Rizatriptan Impurity G
• 1,8-dinitro-pyren

1,8-Dinitropyrene (90%)

CAS: 42397-65-9

Formula: C₁₆H₈N₂O₄

Color and Shape: Solid

Molecular weight: 292.2457

Ref: IN-DA003DS6

1, 8-Dinitropyrene

CAS: 42397-65-9

Formula: C₁₆H₈N₂O₄

Molecular weight: 292.25

Ref: 4Z-P-187002

1,8-Dinitropyrene (90%)

Controlled Product

CAS: 42397-65-9

Formula: C₁₆H₈N₂O₄

Purity: 90%

Color and Shape: Dark Brown

Molecular weight: 292.25

Ref: TR-D480270

1,8-Dinitropyrene

CAS: 42397-65-9

1,8-Dinitropyrene is a genotoxic and mutagenic potential agent. It has been shown to induce nitric oxide synthase activity in rat liver microsomes, which may be due to its ability to activate the redox potential of the cells. 1,8-Dinitropyrene also induces enzyme activities such as p450 and nitroreductase in rat liver microsomes. This chemical has an analytical detection limit of 0.05 ppm and can be used as a marker for environmental exposure. 1,8-Dinitropyrene is genotoxic and carcinogenic in rats but not mice. It has been shown to induce mutations at the thymidine position of calf-thymus DNA and is potent inducer of genetic mutation in vitro.

Formula: C₁₆H₈N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 292.25 g/mol

Ref: 3D-FD146845