CAS 425-51-4

17-(Acetyloxy)pregna-4,6-diene-3,20-dione

Description:

17-(Acetyloxy)pregna-4,6-diene-3,20-dione, commonly known as Medroxyprogesterone acetate (MPA), is a synthetic progestin used in various hormonal therapies. It is characterized by its steroidal structure, which includes a pregnane backbone with specific functional groups that confer its biological activity. MPA is typically a white to off-white crystalline powder, and it is soluble in organic solvents such as ethanol and acetone but has limited solubility in water. The compound exhibits progestational effects, making it effective in regulating menstrual cycles, treating endometriosis, and serving as a contraceptive. Its mechanism of action involves binding to progesterone receptors, leading to changes in gene expression that inhibit ovulation and alter the uterine lining. MPA is also used in hormone replacement therapy and for managing certain types of cancer. Safety and efficacy profiles are well-documented, but potential side effects may include weight gain, mood changes, and increased risk of thromboembolic events. As with any hormonal treatment, it is essential to use MPA under medical supervision.

Formula: C₂₃H₃₀O₄

InChI: InChI=1S/C23H30O4/c1-14(24)23(27-15(2)25)12-9-20-18-6-5-16-13-17(26)7-10-21(16,3)19(18)8-11-22(20,23)4/h5-6,13,18-20H,7-12H2,1-4H3/t18-,19+,20+,21+,22+,23+/m1/s1

InChI key: InChIKey=URXWVWVPMJSAJD-KOORYGTMSA-N

SMILES: O(C(C)=O)[C@@]1(C(C)=O)[C@]2(C)[C@@](CC1)([C@]3([C@](CC2)([C@]4(C)C(C=C3)=CC(=O)CC4)[H])[H])[H]

Synonyms:

• Pregna-4,6-diene-3,20-dione, 17-hydroxy-, acetate
• 17-(Acetyloxy)pregna-4,6-diene-3,20-dione
• 6-Dehydro-17α-acetoxyprogesterone
• 17-Acetoxypregna-4,6-diene-3,20-dione
• Pregna-4,6-diene-3,20-dione, 17-(acetyloxy)-

Chlormadinone Acetate EP Impurity K

CAS: 425-51-4

Formula: C₂₃H₃₀O₄

Color and Shape: White To Off-White Solid

Molecular weight: 370.49

Ref: 4Z-C-6518

6,7-Dehydro-17α-acetoxy Progesterone

CAS: 425-51-4

Formula: C₂₃H₃₀O₄

Color and Shape: Neat

Molecular weight: 370.48

Ref: TR-D229090

6,7-Dehydro-17a-acetoxy progesterone

Controlled Product

CAS: 425-51-4

6,7-Dehydro-17α-acetoxyprogesterone (DHA) is a synthetic steroid that has anti-estrogenic and anti-androgenic effects. It is used as an appetite stimulant in the treatment of anorexia and cachexia. DHA is also used to treat breast cancer in women and men with prostate cancer. The drug can be administered by injection or orally. DHA belongs to a class of drugs known as progestins, which are related to the female sex hormone progesterone. This drug has been found to have sublethal effects on humans, including cardiovascular disorders, liver damage, and bone loss.

Formula: C₂₃H₃₀O₄

Purity: Min. 95%

Molecular weight: 370.48 g/mol

Ref: 3D-ID20958

Chlormadinone Acetate EP Impurity K

CAS: 425-51-4

Formula: C₂₃H₃₀O₄

Molecular weight: 370.49

Ref: ST-EA-CP-P133042