CAS 42935-17-1: PGH2

Description: PGH2, or Prostaglandin H2, is a biologically active lipid compound that plays a crucial role in various physiological processes. It is an intermediate in the biosynthesis of prostaglandins, which are important signaling molecules involved in inflammation, pain, and the regulation of various bodily functions. PGH2 is characterized by its unstable nature, as it readily undergoes further enzymatic conversion to other prostaglandins, such as PGE2 and PGI2, which have distinct biological activities. The compound is typically synthesized from arachidonic acid through the action of cyclooxygenase enzymes. PGH2 is known for its role in mediating inflammatory responses and is involved in the regulation of vascular tone and platelet aggregation. Due to its short half-life and reactivity, PGH2 is not usually found in significant quantities in biological systems but is crucial in the context of prostaglandin synthesis. Its study is important in pharmacology and medicine, particularly in understanding the mechanisms of pain and inflammation and the development of anti-inflammatory drugs.

Formula: C₂₀H₃₂O₅

InChI: InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18-14-19(17)25-24-18)10-7-4-5-8-11-20(22)23/h4,7,12-13,15-19,21H,2-3,5-6,8-11,14H2,1H3,(H,22,23)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1

InChI key: InChIKey=YIBNHAJFJUQSRA-YNNPMVKQSA-N

SMILES: O=C(O)CCCC=CCC1C2OOC(C2)C1C=CC(O)CCCCC

Synonyms:

• (15S)Hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid
• (5Z)-7-{(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid
• (5Z,9α,11α,13E,15S)-9,11-Epidioxy-15-hydroxyprosta-5,13-dien-1-oic acid
• 15-Hydroxy-9α,11α-peroxidoprosta-5,13-dienoic acid
• 2,3-Dioxabicyclo[2.2.1]heptane, prosta-5,13-dien-1-oic acid deriv.
• 7-[6-(3-Hydroxyoct-1-En-1-Yl)-2,3-Dioxabicyclo[2.2.1]Hept-5-Yl]Hept-5-Enoic Acid
• 9,11-Epoxymethano-pgh2
• Endoperoxide H₂
• PGH₂
• Pgh 2
• Prosta-5,13-dien-1-oic acid, 9,11-epidioxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-
• Prosta-5,13-dien-1-oic acid, 9,11-epidioxy-15-hydroxy-, (5Z,9α,11α,13E,15S)-
• Prostaglandin H₂
• Prostaglandin R₂
• Prostaglandin R2
• PGH2

Prostaglandin H2

CAS: 42935-17-1

• Formula: C₂₀H₃₂O₅
• Purity: ≥ 95%
• Color and Shape: Liquid
• Molecular weight: 352.47

Prostaglandin H2

CAS: 42935-17-1

• Formula: C20H32O5
• Purity: >98%
• Color and Shape: In solution, Dry Acetone
• Molecular weight: 352.47

Prostaglandin H2

CAS: 42935-17-1

Prostaglandin H2 (PGH2), initially isolated from the incubation of arachidonic acid with ovine seminal vesicle …

• Formula: C₂₀H₃₂O₅
• Color and Shape: Liquid
• Molecular weight: 352.471