CAS 4330-21-6

Hoffer's chlorosugar

Description:

Hoffer's chlorosugar, identified by its CAS number 4330-21-6, is a chlorinated derivative of a sugar molecule, specifically related to the structure of carbohydrates. This compound typically exhibits characteristics common to chlorinated organic compounds, such as increased reactivity due to the presence of chlorine atoms, which can influence its chemical behavior and interactions. Hoffer's chlorosugar may display unique solubility properties, often being soluble in organic solvents while having limited solubility in water, depending on its specific structure. The presence of chlorine can also affect its biological activity, potentially making it useful in various applications, including medicinal chemistry or as a synthetic intermediate. Additionally, like many chlorinated compounds, it may have implications for environmental and health safety, necessitating careful handling and disposal. Overall, Hoffer's chlorosugar represents an interesting intersection of carbohydrate chemistry and halogenated organic compounds, with potential applications in research and industry.

Formula: C₂₁H₂₁ClO₅

InChI: InChI=1S/C21H21ClO5/c1-13-3-7-15(8-4-13)20(23)25-12-18-17(11-19(22)26-18)27-21(24)16-9-5-14(2)6-10-16/h3-10,17-19H,11-12H2,1-2H3/t17-,18+,19-/m0/s1

InChI key: InChIKey=FJHSYOMVMMNQJQ-OTWHNJEPSA-N

SMILES: C(OC(=O)C1=CC=C(C)C=C1)[C@@H]2[C@@H](OC(=O)C3=CC=C(C)C=C3)C[C@@H](Cl)O2

Synonyms:

• (2R,3S,5R)-5-Chloro-2-[[(4-methylbenzoyl)oxy]methyl]tetrahydrofuran-3-yl] 4-methylbenzoate
• 1-Chloro-2-deoxy-3,5-di-O-p-toluoyl-α-<span class="text-smallcaps">D</span>-erythro-pentofuranose
• 1-Chloro-2-deoxy-3,5-di-O-p-toluoyl-α-<span class="text-smallcaps">D</span>-ribose
• 1-Chloro-2-deoxy-3,5-di-O-toluoyl-D-ribofuranose
• 1-Chloro-2-deoxy-3,5-di-O-toluoyl-a-<span class="text-smallcaps">D</span>-ribofuranose
• 1-alpha-Chloro-3,5-di-O-(4-toluoyl)-2-deoxy-D-ribofuranose
• 1-α-Chloro-3,5-ditoluoyl-2-deoxy-<span class="text-smallcaps">D</span>-ribose
• 2-Deoxy-3,5-di-O-p-toluoyl-α-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl chloride
• 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate)
• 2-deoxy-3,5-bis-O-(4-methylbenzoyl)-alpha-D-erythro-pentofuranosyl chloride
• 2-deoxy-3,5-bis-O-(4-methylbenzoyl)pentofuranosyl chloride
• 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride
• 3,5-Di-O-p-toluyl-2-deoxy-α-<span class="text-smallcaps">D</span>-ribofuranosyl chloride
• 3,5-Di-O-toluoyl-α-1-chloro-2-deoxy-<span class="text-smallcaps">D</span>-ribofuranose
• <span class="text-smallcaps">D</span>-erythro-Pentofuranosyl chloride, 2-deoxy-, di-p-toluate, α-
• Hoffer's chlorosugar
• Hoffer's sugar
• Hoffer's α-chlorosugar
• NSC 148837
• p-Toluic acid, diester with 2-deoxy-α-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl chloride
• α-<span class="text-smallcaps">D</span>-erythro-Pentofuranosyl chloride, 2-deoxy-, 3,5-bis(4-methylbenzoate)
• α-<span class="text-smallcaps">D</span>-erythro-Pentofuranosyl chloride, 2-deoxy-, bis(4-methylbenzoate)
• α-D-erythro-Pentofuranosyl chloride, 2-deoxy-, bis(4-methylbenzoate)
• 3,5-Di-O-p-toluyl-2-deoxy-α-D-ribofuranosyl chloride
• α-D-erythro-Pentofuranosyl chloride, 2-deoxy-, 3,5-bis(4-methylbenzoate)
• p-Toluic acid, diester with 2-deoxy-α-D-erythro-pentofuranosyl chloride

2-Deoxy-α-D-Erythropentofuranosyl Chloride 3,5-Bis(4-Methylbenzoate)

CAS: 4330-21-6

Formula: C₂₁H₂₁ClO₅

Purity: 90%

Color and Shape: Solid

Molecular weight: 388.8414

Ref: IN-DA00DE39

2-Deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

CAS: 4330-21-6

2-Deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride

Purity: 90%

Molecular weight: 388.85g/mol

Ref: 54-OR97914

3,5-Di-O-(p-toluyl)-2-deoxy-D-ribofuranosyl chloride

CAS: 4330-21-6

Formula: C₂₁H₂₁ClO₅

Purity: ≥ 90.0%

Color and Shape: White, off-white or pink powder

Molecular weight: 388.84

Ref: 7W-GC0348

Hoffer's chlorosugar

CAS: 4330-21-6

Purity: 90.0%

Color and Shape: Solid, Powder

Molecular weight: 388.8399963378906

Ref: 10-F233156

1-Chloro-2-deoxy-3,5-di-O-toluoyl-a-D-ribofuranose

CAS: 4330-21-6

1-Chloro-2-deoxy-3,5-di-O-toluoyl-a-D-ribofuranose (also known as Hoffer’s chlorosugar) is a synthetic building block used in nucleic acid research to afford an array of both alpha and beta linked 2’-deoxyribose derivatives. Naturally occurring nucleosides are typically beta linked and the efficient synthesis of alpha linked analogues, which are often more stable, offers access to interesting variations in 3D structure and biochemical reactivity.

Formula: C₂₁H₂₁ClO₅

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 388.84 g/mol

Ref: 3D-MC02788