CAS 433249-94-6

Formula: C17H17NO

InChI: InChI=1S/C17H17NO/c1-13-8-9-14(2)16(12-13)18-11-10-17(19)15-6-4-3-5-7-15/h3-12,18H,1-2H3/b11-10+

InChI key: SARYOFMRLSHZFE-ZHACJKMWSA-N

SMILES: CC1=CC(=C(C=C1)C)N/C=C/C(=O)C2=CC=CC=C2

TRAF-STOP inhibitor 6877002

CAS: 433249-94-6

TRAF-STOP inhibitor 6877002

Formula: C₁₇H₁₇NO

Purity: 99.5%

Molecular weight: 251.32

Ref: 54-BUP11546

TRAF-STOP inhibitor 6877002

CAS: 433249-94-6

Formula: C₁₇H₁₇NO

Purity: 98%

Molecular weight: 251.3230

Ref: IN-DA01E4HF

TRAF-STOP inhibitor 6877002

CAS: 433249-94-6

3-((2,5-Dimethylphenyl)amino)-1-phenylprop-2-en-1-one

Formula: C₁₇H₁₇NO

Purity: 98%

Molecular weight: 251.32

Ref: IN-DG01175392

3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one

Controlled Product

CAS: 433249-94-6

Applications 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one functions as CD40-TRAF6 inhibitors. Inhibition of CD40 signalling pathway seems a better way to ameliorate inflammatory diseases, like the inflammation in models of peritonitis and sepsis.
References Zarzycka, B., et al.: J. Chem. Inf. Model., 55, 294 (2015);

Formula: C₁₇H₁₇NO

Color and Shape: Neat

Molecular weight: 251.32

Ref: TR-D457460

TRAF-STOP inhibitor 6877002

CAS: 433249-94-6

TRAF-STOP inhibitor 6877002 is a molecule inhibitor that inhibits the activity of signalling molecules in chronic inflammation, atherosclerosis, and cardiac hypertrophy. TRAF-STOP inhibitor 6877002 is an inhibitor group that blocks the signalling pathways involved in cardiac function. It has been shown to inhibit cardiac hypertrophy by inhibiting the signaling pathways mediated by TNF-α, IL-1β, and IL-6. This drug also reduces systolic dysfunction in heart failure patients with reduced ejection fraction by suppressing myocardial fibrosis.

Formula: C₁₇H₁₇NO

Purity: Min. 95%

Molecular weight: 251.32 g/mol

Ref: 3D-ISA24994

TRAF-STOP inhibitor 6877002

CAS: 433249-94-6

TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.

Formula: C₁₇H₁₇NO

Purity: 99.76%

Color and Shape: Yellow Solid

Molecular weight: 251.323

Ref: TM-T17157